Chong Daniel Tt, Andreotti Felicita, Verhamme Peter, Dalal Jamshed, Uaprasert Noppacharn, Wang Chun-Chieh, On Young Keun, Li Yi-Heng, Jiang Jun, Hasegawa Koji, Almuti Khalid, Bai Rong, Lo Sidney Th, Krittayaphong Rungroj, Lee Lai Heng, Quek David Kl, Johar Sofian, Seow Swee-Chong, Hammett Christopher J, Tan Jack Wc
National Heart Centre Singapore.
Fondazione Policlinico Universitario A Gemelli IRCCS Rome, Italy.
Eur Cardiol. 2021 May 28;16:e23. doi: 10.15420/ecr.2020.43. eCollection 2021 Feb.
The disease burden of AF is greater in Asia-Pacific than other areas of the world. Direct oral anticoagulants (DOACs) have emerged as effective alternatives to vitamin K antagonists (VKA) for preventing thromboembolic events in patients with AF. The Asian Pacific Society of Cardiology developed this consensus statement to guide physicians in the management of AF in Asian populations. Statements were developed by an expert consensus panel who reviewed the available data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting 17 statements provide guidance on the assessment of stroke risk of AF patients in the region, the appropriate use of DOACs in these patients, as well as the concomitant use of DOACs and antiplatelets, and the transition to DOACs from VKAs and vice versa. The periprocedural management of patients on DOAC therapy and the management of patients with bleeding while on DOACs are also discussed.
亚太地区房颤的疾病负担比世界其他地区更重。直接口服抗凝剂（DOACs）已成为维生素K拮抗剂（VKA）在预防房颤患者血栓栓塞事件方面的有效替代药物。亚太心脏病学会制定了本共识声明，以指导医生对亚洲人群房颤的管理。声明由一个专家共识小组制定，该小组审查了来自亚太地区患者的现有数据。制定共识声明后进行了在线投票。最终形成的17条声明为该地区房颤患者的卒中风险评估、这些患者中DOACs的合理使用、DOACs与抗血小板药物的联合使用，以及从VKA转换为DOACs或反之的转换提供了指导。还讨论了接受DOAC治疗患者的围手术期管理以及使用DOACs时出血患者的管理。
