克唑替尼相关肾囊肿的发生可能与ALK阳性非小细胞肺癌患者无进展生存期延长有关：病例报告及文献综述

Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with -positive non-small-cell lung cancer: Case report and review of the literature.

作者信息

Wiest Nathaniel E, Tzou Katherine S, Olson Matthew T, Herchko Steven M, Bajalia Essa M, Thiel David D, Lou Yanyan, Zhao Yujie, Manochakian Rami

机构信息

Department of Internal Medicine Mayo Clinic Florida Jacksonville FL USA.

Department of Radiation Oncology Mayo Clinic Florida Jacksonville FL USA.

出版信息

Clin Case Rep. 2021 Jun 10;9(6):e04278. doi: 10.1002/ccr3.4278. eCollection 2021 Jun.

Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.