Ducange Pietro, Verdina Tommaso, Stiro Fabio, Grottola Antonella, Orlando Gabriella, Delvecchio Giancarlo, Mastropasqua Rodolfo
Institute of Ophthalmology, University of Modena and Reggio Emilia, Modena, Italy.
Microbiology and Virology Unit, Azienda Ospedaliero-Universitaria Policlinico Modena, Modena, Italy.
Med Mycol Case Rep. 2021 May 25;33:1-4. doi: 10.1016/j.mmcr.2021.05.001. eCollection 2021 Sep.
We report an atypical presentation of keratitis which unusually presented in a 85-year-old patient with a corneal ulcer with an anterior segment inflammation and . Despite negative culture and unspecific results from panfungal PCR-based sequencing, the patient was treated for a presumed fungal infection. Following clinical deterioration an emergency surgical intervention with apposition of a corneal patch was performed. Infection resolution was achieved following the introduction of systemic voriconazole to the topical one.
我们报告了一例角膜炎的非典型表现，该病例罕见地出现在一名85岁患有角膜溃疡且伴有前段炎症的患者身上。尽管培养结果为阴性且基于泛真菌PCR测序的结果不具特异性，但该患者仍因疑似真菌感染而接受治疗。在临床病情恶化后，进行了紧急手术干预，植入了角膜补片。在将全身用伏立康唑改为局部用药后，感染得到控制。
