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[Somatotropin increases the rate of incorporation of thymidine into DNA and amino acids into proteins of thymocyte subpopulations isolated in a ficoll-urografin gradient from hypothyroid rats].

作者信息

Litvienko E A, Martynenko F P

出版信息

Ukr Biokhim Zh (1978). 1988 May-Jun;60(3):85-8.

PMID:3413847
Abstract

The summarized suspension of thymocytes was separated into subpopulations in the ficoll-urografin gradient density and 6 fractions of thymocytes were obtained. Experiments in vivo showed that under hypothyreosis incorporation of 3H-thymidine into DNA thymocytes, which were isolated in the ficoll-urografin density of 1.065, 1.071, 1.073 and residue is found to be increased than that of intact rats by 72, 35, 47 and 24%, respectively, and incorporation of 14C-amino acids into thymocyte proteins--by 44, 29, 37 and 45%, respectively. Somatotropin normalizes incorporation of the mentioned precursors into the corresponding biopolymers.

摘要

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