Joshi Rajiv
Dermatologist and Dermatopathologist, P. D. Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai, India.
Indian Dermatol Online J. 2012 Sep;3(3):215-9. doi: 10.4103/2229-5178.101826.
Schwannomas are benign peripheral nerve sheath neoplasms composed almost entirely of Schwann cells and are diagnosed histopathologically by the presence of singular architectural patterns called Antoni A and Antoni B areas. These were described first in 1920 by the Swedish neurologist Nils Antoni. The Antoni A tissue is highly cellular and made up of palisades of Schwann cell nuclei, a pattern first described in 1910 by the Uruguayan neuro-pathologist Jose Verocay and are known as Verocay bodies. This article describes the structure and appearance of Verocay bodies and Antoni A and B areas with a brief biographical introduction of the men who described these patterns.
施万细胞瘤是几乎完全由施万细胞组成的良性周围神经鞘瘤,通过存在称为Antoni A区和Antoni B区的独特结构模式在组织病理学上进行诊断。这些模式于1920年由瑞典神经学家尼尔斯·安东尼首次描述。Antoni A组织细胞高度密集,由施万细胞核的栅栏状排列组成,这种模式于1910年由乌拉圭神经病理学家何塞·韦罗凯首次描述,被称为韦罗凯小体。本文描述了韦罗凯小体以及Antoni A区和B区的结构和外观,并简要介绍了描述这些模式的人物生平。