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采用人心包补片闭合大型腰骶部脊膜脊髓膨出缺损:一例报告。

Closure of a large lumbosacral myelomeningocele defect with a human pericardial graft: a case report.

机构信息

Neurosurgery Department of Garrahan Hospital, Buenos Aires, Argentina.

出版信息

Childs Nerv Syst. 2022 Apr;38(4):851-854. doi: 10.1007/s00381-021-05262-0. Epub 2021 Jun 18.

Abstract

INTRODUCTION

Myelomeningocele (MMC) is a complex congenital defect resulting from incomplete closure of the neural tube. The aim of this study is to present an unusual technique for the closure of a large defect.

CASE REPORT

Here we report a patient that was prenatally diagnosed with MMC. At birth, a skin defect of approximately 5 x 7 cm was observed. To repair the defect, a Z-plasty was performed; however, necrosis of the flap developed 3 days after the surgery. The devitalized tissue was removed, and a human pericardial graft was used to cover the defect.

DISCUSSION

Different techniques have been described for the repair of MMC with a large skin defect, such as rotation skin flaps as well as synthetic and biological grafts. In our patient, a new technique without prior experience consisting of the application of human cadaveric pericardial graft was used with good results and no complications.

CONCLUSION

Closure of MMC is often a surgical challenge. Here we describe a surgical technique for the closure of large skin defects.

摘要

简介

脊髓脊膜膨出(MMC)是一种复杂的先天性神经管缺陷,由神经管不完全闭合引起。本研究旨在介绍一种用于闭合大型缺陷的独特技术。

病例报告

我们在此报告一例产前诊断为 MMC 的患者。出生时,观察到约 5 x 7 厘米的皮肤缺损。为了修复该缺陷,进行了 Z 成形术;然而,术后 3 天,皮瓣发生坏死。坏死组织被切除,用人的心包膜移植物覆盖缺损。

讨论

已有多种技术用于修复伴有大皮肤缺损的 MMC,例如旋转皮瓣以及合成和生物移植物。在我们的患者中,使用了一种没有先前经验的新技术,即应用人尸体的心包膜移植物,取得了良好的效果且无并发症。

结论

MMC 的闭合通常是一项具有挑战性的手术。在此,我们描述了一种用于闭合大型皮肤缺损的手术技术。

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