Zoller D P, Jurica J V, Gould S H, Weinstein-Mayer S
Department of Family Medicine, University of Illinois College of Medicine, Rockford.
J Am Board Fam Pract. 1988 Apr-Jun;1(2):98-100.
Traditionally, screening for gestational diabetes mellitus (GDM) has been done only for those women with identifiable risk factors. To determine the value of screening all pregnant women, 363 consecutive patients were tested for GDM using a glucose challenge test (GCT). The test measured plasma glucose 1 hour after administration of a 50-gram oral glucose load. Those patients with a plasma glucose greater than 140 mg/dL were given a standard 3-hour glucose tolerance test (GTT) using 100 g of oral glucose. Patients with risk factors were compared with those without risk factors. There was no significant difference between the two groups for number of abnormal 3-hour GTTs. We conclude that in order to identify GDM, all pregnant patients must be screened. Universal screening was found to be simple and cost effective.
传统上，仅对那些具有可识别风险因素的女性进行妊娠期糖尿病（GDM）筛查。为了确定对所有孕妇进行筛查的价值，对363例连续的患者使用葡萄糖耐量试验（GCT）进行GDM检测。该试验在给予50克口服葡萄糖负荷后1小时测量血浆葡萄糖。血浆葡萄糖大于140mg/dL的患者使用100克口服葡萄糖进行标准的3小时葡萄糖耐量试验（GTT）。将有风险因素的患者与无风险因素的患者进行比较。两组之间异常3小时GTT的数量没有显著差异。我们得出结论，为了识别GDM，所有孕妇都必须进行筛查。发现普遍筛查简单且具有成本效益。
