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急性肾损伤作为沙特阿拉伯吉达阿卜杜勒阿齐兹大学医院脑卒中患者脑血管病转归的危险因素:一项回顾性队列研究。

Acute Kidney Injury as a Risk Factor for Cerebrovascular Disease Outcome among Patients Presenting with Stroke in King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Cohort Study.

机构信息

Department of Nephrology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Department of Family and Community Medicine, King Abdulaziz University, Rabigh, Saudi Arabia; Department of Community and Occupational Medicine, Al Azhar University, Cairo, Egypt.

出版信息

Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):60-68. doi: 10.4103/1319-2442.318549.

Abstract

Patients suffering from stroke may develop different complications including acute kidney injury (AKI). AKI affects mortality among the stroke patients. The association between stroke and AKI despite extensive research has been not completely understood. The study aimed to determine an AKI as an independent poor risk factor of cerebrovascular disease outcome among the stroke patients. Our objectives were to estimate AKI incidence among stroke patients at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia, between 2013 and 2017 and assess the major risk factors related to AKI among stroke patients. The research population was sourced from the publicly available KAUH records from 2013 to 2017. The total number of stroke cases was 717 with a mean age of 63.94 ± 15.70 years. As many as 83.5% of cases had no AKI and 16.5% were suffered from AKI among total stroke patients studied. Furthermore, 74.1% of stroke patients were alive compared to 25.9% reported dead. The study concluded that AKI incidence is higher in stroke patients after admission immediately or during hospitalization. As such, the renal function file could be used as an early indicator upon stroke patients' admission to health-care facilities. Prevention and control of AKI seem to be very important among patients with stroke.

摘要

中风患者可能会出现不同的并发症,包括急性肾损伤(AKI)。AKI 会影响中风患者的死亡率。尽管进行了广泛的研究,但中风与 AKI 之间的关联仍未完全理解。本研究旨在确定 AKI 是否是中风患者脑血管病结局的独立不良风险因素。我们的目的是估计 2013 年至 2017 年间在沙特阿拉伯吉达的阿卜杜勒阿齐兹国王大学医院(KAUH)中风患者中 AKI 的发生率,并评估与中风患者 AKI 相关的主要危险因素。研究人群来自 2013 年至 2017 年公开的 KAUH 记录。共有 717 例中风病例,平均年龄为 63.94±15.70 岁。在所研究的所有中风患者中,多达 83.5%的患者没有 AKI,16.5%的患者患有 AKI。此外,与报告死亡的 25.9%相比,有 74.1%的中风患者存活。研究结论是,中风患者在入院后立即或住院期间 AKI 的发生率更高。因此,肾功能文件可以作为中风患者入住医疗机构时的早期指标。预防和控制 AKI 似乎对中风患者非常重要。

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