罗哌卡因：一种用于耳鼻喉科实践的新型局部麻醉药。
Ropivacaine: A Novel Local Anaesthetic Drug to Use in Otorhinolaryngology Practice.
作者信息
Ahilasamy Nagalingeswaran, Dinesh Kumar Rajendran, Nayagam Hem Anand, Shanmuganandam Omprakash, Vaibhavi K R, Modak Vishakha
机构信息
Ahilasamy ENT Centre, Chennai, Tamil Nadu 600 042 India.
Department of ENT and Head-Neck Surgery, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka 560074 India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2021 Jun;73(2):267-270. doi: 10.1007/s12070-020-02309-7. Epub 2021 Jan 4.
Abstract
Ropivacaine is a long-acting amide local anaesthetic agent which has a significant vasoconstrictive property, long duration of action, least central nervous system and cardiac complications due to the pure (S)-enantiomer property by reversible inhibition of sodium ion influx in nerve fibres. By using additives the duration of analgesia may be prolonged. Ropivacaine has been used routinely in our otorhinolaryngology procedures since 2010 (10 years). The present article details the clinical applications of ropivacaine and its current place as a local anaesthetic in otorhinolaryngology practice.
摘要
罗哌卡因是一种长效酰胺类局部麻醉药，具有显著的血管收缩特性、作用时间长，由于其纯（S）-对映体特性，通过可逆性抑制神经纤维中的钠离子内流，导致中枢神经系统和心脏并发症最少。通过使用添加剂，镇痛时间可能会延长。自2010年（10年）以来，罗哌卡因已在我们的耳鼻喉科手术中常规使用。本文详细介绍了罗哌卡因的临床应用及其作为局部麻醉药在耳鼻喉科实践中的当前地位。
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