Oi Samira Shizuko Parreão, Muniz Monique Pereira Rêgo, Faria Igor Murad, Filho Natalino Salgado, de Brito Dyego José Araújo, Lages Joyce Santos, Lauande Letícia Pádua, Oliveira Thina Klicia Mendonça, Cunha Kaile de Araújo, Neves Precil Diego Miranda de Menezes, Silva Gyl Eanes Barros
University Hospital, Federal University of Maranhão (HU-UFMA), São Luís, Brazil.
Nephrology Division, Medical School, University of São Paulo (FM-USP), São Paulo, Brazil.
Front Pediatr. 2021 Jun 4;9:659069. doi: 10.3389/fped.2021.659069. eCollection 2021.
Clinical presentations of the novel coronavirus (SARS-CoV-2) infection are quite varied, ranging from asymptomatic conditions to potentially fatal disease. The kidney is one of the affected targets of coronavirus disease (COVID-19) complications, and renal dysfunction is a significant prognostic factor for mortality. This report describes a series of clinical complications in a previously healthy child who developed nephritic syndrome with a concomitant SARS-CoV-2 infection. These complications include acute kidney injury that progressed to chronicity, multisystemic inflammatory syndrome, Kawasaki-like syndrome, and thrombotic microangiopathy.
新型冠状病毒(SARS-CoV-2)感染的临床表现多种多样,从无症状感染到可能致命的疾病。肾脏是冠状病毒病(COVID-19)并发症的受累靶器官之一,肾功能不全是死亡率的重要预后因素。本报告描述了一名先前健康的儿童在感染SARS-CoV-2的同时出现肾病综合征的一系列临床并发症。这些并发症包括进展为慢性的急性肾损伤、多系统炎症综合征、川崎样综合征和血栓性微血管病。