Lalević-Vasić B, Polić D
Clinique Dermato-vénéréologique, Faculté de Médecine de Belgrade, Yougoslavie.
Ann Dermatol Venereol. 1988;115(4):433-40.
A case of ringed hair studied by light and electron microscopy is reported. The patient, a 20-year old girl, had been presenting with the hair abnormality since birth. At naked eye examination the hairs were dry, 6 to 7 cm long, and they showed dull and shining areas giving the scalp hair a scintillating appearance (fig. 1). Several samples of hair were taken and examined by light microscopy under white and polarized light. Hair shafts and cryo-fractured surfaces were examined by scanning electron microscopy. RESULTS. 1. Light microscopy. Lesions were found in every hair examined. There were abnormal, opaque and fusiform areas alternating with normal areas all along the hair shaft (fig. 2). The abnormal areas resulted from intracortical air-filled cavities. Fractures similar to those of trichorrhexis nodosa were found in the opaque areas of the distal parts of the hairs. 2. Scanning electron microscopy. A. Hair shaft surface. The abnormal areas showed a longitudinal, "curtain-like" folding of the cuticular cells which had punctiform depressions on their surface and worn free edges (fig. 4, 5, 6); trichorrhexis-type fractures were seen in the distal parts of the hair shafts (fig. 7, 8). Normal areas regularly presented with longitudinal, superficial, short and non-systematized depressions (fig. 9); the cuticular cells were worn, and there were places where the denuded cortex showed dissociated cortical fibres (fig. 10).(ABSTRACT TRUNCATED AT 250 WORDS)
报告了一例通过光学显微镜和电子显微镜研究的环状毛发病例。患者为一名20岁女孩，自出生以来就一直存在毛发异常。肉眼检查时，毛发干燥，长6至7厘米，有暗淡和闪亮区域，使头皮毛发呈现闪烁外观（图1）。采集了几根毛发样本，在白光和偏振光下进行光学显微镜检查。对毛干和冷冻断裂面进行扫描电子显微镜检查。结果：1. 光学显微镜检查。在每根检查的毛发中均发现病变。沿着毛干有异常、不透明的梭形区域与正常区域交替出现（图2）。异常区域是由皮质内充满空气的腔隙导致的。在毛发远端不透明区域发现了类似于结节性脆发症的断裂。2. 扫描电子显微镜检查。A. 毛干表面。异常区域显示角质形成细胞呈纵向“帘状”折叠，其表面有点状凹陷且边缘磨损（图4、5、6）；在毛干远端可见脆发症样断裂（图7、8）。正常区域通常有纵向、浅表、短且无规律的凹陷（图9）；角质形成细胞磨损，在某些部位裸露的皮质显示出解离的皮质纤维（图10）。（摘要截取自250字）
