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[先天性毛发干折断。先天性毛发生长障碍的扫描电子显微镜研究]

[Trichorrhexis congenita. Scanning electron microscopic studies on a congenital disorder of hair growth].

作者信息

Wolff H H, Vigl E, Braun-Falco O

出版信息

Hautarzt. 1975 Nov;26(11):576-80.

PMID:1205844
Abstract
  1. A congenital disturbance of hair growth belonging to the "trichorrhexis nodosa" group is described. Clinically, abnormal hair fragility since birth was the leading symptom. There was no detectable amino-aciduria. 2. The scanning electron microscope (SEM) reveals localized alterations of the hair shafts. These are irregularities of the cuticular pattern, partial fractures of the cortical filament bundles, and complete fractures with broom-like splintering of the hair ends. 3. There is no generally accepted definition of the symptom or the disease of "trichorrhexis nodosa". Further SEM analysis and collection of such hair anomalies is proposed. As in the case described here no "nodes" of the hair shaft were observed, it is presented as "trichorrhexis conginita".
摘要
  1. 本文描述了一种属于“结节性脆发病”组的先天性毛发发育障碍。临床上,自出生起毛发异常脆弱是主要症状。未检测到氨基酸尿症。2. 扫描电子显微镜(SEM)显示毛干存在局部改变。这些改变包括表皮模式不规则、皮质细丝束部分断裂以及毛发末端呈扫帚状分裂的完全断裂。3. 对于“结节性脆发病”的症状或疾病,目前尚无普遍接受的定义。建议进一步进行扫描电子显微镜分析并收集此类毛发异常情况。由于在此病例中未观察到毛干的“结节”,故将其呈现为“先天性脆发病”。

引用本文的文献

1
Primary Congenital Trichorrhexis Nodosa with Nevus Achromicus: A Rare Presentation.
Int J Trichology. 2018 Jul-Aug;10(4):186-188. doi: 10.4103/ijt.ijt_7_18.
2
Professor Dr. Dr. h. c. Otto Braun-Falco.
Arch Dermatol Res. 1987;279 Suppl:S4-23. doi: 10.1007/BF00585915.

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