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用于改进三维成像的虚拟深度扫描多层叠层成像技术。

Virtual depth-scan multi-slice ptychography for improved three-dimensional imaging.

作者信息

Xing Zhenjiang, Xu Zijian, Zhang Xiangzhi, Chen Bo, Guo Zhi, Wang Jian, Wang Yong, Tai Renzhong

出版信息

Opt Express. 2021 May 24;29(11):16214-16227. doi: 10.1364/OE.422214.

DOI:10.1364/OE.422214
PMID:34154189
Abstract

Multi-slice ptychography (MSP) is a fast three-dimensional ptychography technology developed on the basis of conventional ptychography. With this method, three-dimensional imaging can be achieved without rotating the sample. The prototype multi-slice algorithm can only reconstruct three-dimensional samples with a limited number of slices, which greatly limits the depth range and resolution of sample imaging. Here we reported a virtual depth-scan scheme of MSP in which a thick sample is scanned virtually in the depth direction across its whole thickness range within the reconstruction process, thereby eliminating the restriction on slice number and potentially improving the depth resolution of MSP. This new approach also improves the flexibility of multi-slice ptychography. Both the simulation and experimental results validate the feasibility of our new approach.

摘要

多切片叠层成像术(MSP)是一种基于传统叠层成像术发展而来的快速三维叠层成像技术。采用这种方法,无需旋转样品即可实现三维成像。最初的多切片算法只能重建具有有限切片数量的三维样品,这极大地限制了样品成像的深度范围和分辨率。在此,我们报道了一种MSP的虚拟深度扫描方案,即在重建过程中对厚样品在深度方向上跨越其整个厚度范围进行虚拟扫描,从而消除了对切片数量的限制,并有可能提高MSP的深度分辨率。这种新方法还提高了多切片叠层成像术的灵活性。模拟和实验结果均验证了我们新方法的可行性。

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