General Surgery Department, The Affiliated Qingdao Municipal Hospital of Qingdao University, Qingdao, China.
Ann Palliat Med. 2021 Jun;10(6):7132-7137. doi: 10.21037/apm-21-1098. Epub 2021 Jun 15.
It is rare that Acute appendicitis (AA) caused by metastatic gastric adenocarcinoma is seen in the clinic. The underling mechanism is not clear, and the prognoses of these patients have been discrepant. Herein, we have presented a case of this disease seen in our clinic and summarized 7 similar previously reported cases. We reported the case of a 33-year-old female patient who presented with gastric cancer (GC) metastasis to the appendix that was found incidentally in the emergency surgery for AA with evidence of multi-site metastases. The final pathology of endoscopic biopsy and positron emission tomography-computed tomography (PET-CT) confirmed late-stage GC with multi-site metastases. Chemotherapy and radiotherapy were taken after diagnosed, and the patient died about 7 months after appendicectomy. We also reviewed 7 case-reports on GC metastasis to the appendix. The metastasis was symptomatic in 4 cases, and appendectomy was performed in all cases. The prognosis of the cases varied considerably. There was a total of 8 cases included in this paper. We discussed the diagnosis and the potential route of appendiceal metastasis from GC. Of the 8 cases, 6 had a history of GC. We also examined the prognosis of the cases and the benefit of performing appendectomy in every gastrectomy.
临床上罕见转移性胃腺癌引起的急性阑尾炎（AA）。其潜在机制尚不清楚，这些患者的预后存在差异。在此，我们报告了我院收治的 1 例该病患者，并总结了之前报道的 7 例类似病例。我们报告了 1 例 33 岁女性患者，因 AA 行急诊手术时偶然发现胃癌（GC）转移至阑尾，且有多处转移证据。内镜活检和正电子发射断层扫描-计算机断层扫描（PET-CT）的最终病理证实为晚期 GC 伴多处转移。诊断后进行化疗和放疗，阑尾切除术后约 7 个月患者死亡。我们还回顾了 7 例 GC 转移至阑尾的病例报告。4 例有症状，所有病例均行阑尾切除术。病例的预后差异很大。本文共纳入 8 例。我们讨论了从 GC 发生阑尾转移的诊断和潜在途径。8 例中有 6 例有 GC 病史。我们还检查了每个胃癌患者行阑尾切除术后的病例预后和获益。
