University of Amsterdam, The Netherlands.
Leo Kannerhuis (Youz/Parnassiagroup), The Netherlands.
Autism. 2022 Jan;26(1):217-229. doi: 10.1177/13623613211020183. Epub 2021 Jun 21.
Autistic adults without a suspected intellectual disability reported several motor features such as having tremors, and stiffness in one's legs which are considered to be part of a complex of motor features called parkinsonism. This so-called parkinsonism was remarkably prevalent in middle-aged and older autistic adults in two independent studies (Dutch study: 50-81 years, 183 males, 113 females, all adulthood diagnoses; the USA study: 50-83 years, 110 females, 109 males, majority adulthood diagnosis). Parkinsonism can be part of the progressive motor disease-Parkinson's disease. Therefore, it is important that future studies, including in-person neurological assessment, determine if (and if so, why) autistic adults who report these motor features are at increased risk for developing Parkinson's disease.
自闭症成年患者报告了一些运动特征,如震颤和腿部僵硬,这些被认为是一种被称为帕金森病的运动特征复杂症状的一部分。在两项独立的研究中,中年和老年自闭症成年患者中这种所谓的帕金森病非常普遍(荷兰研究:50-81 岁,183 名男性,113 名女性,均为成年诊断;美国研究:50-83 岁,110 名女性,109 名男性,多数为成年诊断)。帕金森病可能是进行性运动疾病——帕金森病的一部分。因此,未来的研究,包括亲自进行神经学评估,确定(如果是,为什么)报告这些运动特征的自闭症成年患者是否有更高的患帕金森病的风险,这一点很重要。