Engelmann C, Stier M, Voigt H, Kaltwasser K, Danzmann E, Franz W D, Riesner R, Krüger A
Z Exp Chir. 1977;10(6):368-83.
Undesired effects of nonspecific immunosuppression may be delimited by individual dosage. Early recognition of allograft rejection is the presupposition for that steering. As long as immunologic test methods require a great expense of equipment, personnel, and time, and as other methods (bronchospirometry, lung puncture) after lung transplantation additionally endanger the recipient, clinical routine examinations are particularly important, primarly thorax x-ray examinations. The authors report on serial chest radiographs during the courses after 71 unilateral orthotopic allogenic pulmonary transplantations in dogs with regard to the findings at obduction. Possibilities of differential diagnosis shall be found by that, and the limits of interpreting x-ray films after lung transplantation shall be disclosed. Certain distinctive marks in the x-ray findings indicate the various possible complications; they can not be relied upon, however, when they only extend to the graft (hemorrhage, infection, rejection).
非特异性免疫抑制的不良影响可通过个体化剂量加以限定。同种异体移植物排斥反应的早期识别是进行这种调控的前提。只要免疫检测方法需要耗费大量的设备、人力和时间，并且肺移植后的其他方法（支气管肺量测定法、肺穿刺）会额外危及受者，那么临床常规检查就尤为重要，主要是胸部X线检查。作者报告了71例犬单侧原位同种异体肺移植术后过程中的系列胸部X线片，并与尸检结果进行了对照。通过这样做应能找到鉴别诊断的方法，并揭示肺移植后X线片解读的局限性。X线检查结果中的某些特征性表现提示了各种可能的并发症；然而，当这些表现仅局限于移植物（出血、感染、排斥反应）时，不能仅依赖它们进行诊断。
