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基于改进的泰曼-格林干涉仪测量正常人眼的眼轴长度。

The measurement of ocular axial length in normal human eyes based on an improved Twyman-Green interferometer.

机构信息

Institute of Biomedical Optics and Optometry, Key Lab of Medical Optical Technology and Instruments, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, China.

Engineering Research Center of Optical Instrument and System, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, China.

出版信息

J Biophotonics. 2021 Oct;14(10):e202100021. doi: 10.1002/jbio.202100021. Epub 2021 Jul 12.

DOI:10.1002/jbio.202100021
PMID:34159745
Abstract

In order to meet the demands of myopia prevention, as well as the increasing needs of measurement for refractive and cataract operations in China, a new axial length (AL) measurement system combining an improved Twyman-Green interferometer with digital signal processing has been established. The ALs of 33 eyes of different optical refractive subjects (-8.50 ~ 0.50 D) were measured with the New AL and intraocular lens (IOL) master. The repeatability of measurements with the New AL was assessed using coefficient of variation (CoV) and intra-group correlation coefficient (ICC). Comparison, correlation, linear regression and agreement of AL between devices were analyzed. There was good repeatability (CoV = 0.0617%, ICC = 0.9999) with the New AL and great agreement has been obtained with both devices. These show that the New AL is capable of providing precise AL values over the normal AL range compared to the IOL master, and indicate that the New AL developed can be used for routine clinical AL measurements.

摘要

为了满足近视防控的需求,以及满足中国屈光和白内障手术日益增长的测量需求,我们建立了一种新的眼轴(AL)测量系统,该系统将改进的 Twyman-Green 干涉仪与数字信号处理相结合。使用新的 AL 和人工晶状体(IOL) master 测量了 33 只不同光学屈光主体(-8.50~0.50 D)的 AL。使用变异系数(CoV)和组内相关系数(ICC)评估新的 AL 测量的重复性。分析了设备之间的 AL 比较、相关性、线性回归和一致性。新的 AL 具有良好的重复性(CoV=0.0617%,ICC=0.9999),与两种设备都具有很好的一致性。这些表明,与 IOL master 相比,新的 AL 能够在正常 AL 范围内提供精确的 AL 值,并表明所开发的新的 AL 可用于常规临床 AL 测量。

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