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[热疗时肺气血屏障的变化]

[Changes in the blood-air barrier of the lungs in hyperthermia].

作者信息

Seredenko M M, Moĭbenko A A, Rozova E V, Grabovskiĭ L A

出版信息

Biull Eksp Biol Med. 1988 Aug;106(8):235-8.

PMID:3416062
Abstract

The influence of hyperthermia on the ultrastructure of lung air-blood barrier (ABB) was studied in experiments on dogs. It was shown that in hyperthermia both mean arithmetic and mean harmonic thickness of ABB were increased. The lung capillary endothelial layer was the most thick ABB layer, in which severe micropinocytosis could be observed. Marked destructive changes were noted in lung alveolar epithelial ABB layer up to the appearance of cell content in alveolar space and denudation of the epithelial basal membrane.

摘要

在犬类实验中研究了热疗对肺气血屏障(ABB)超微结构的影响。结果表明,热疗时ABB的算术平均厚度和调和平均厚度均增加。肺毛细血管内皮细胞层是ABB最厚的一层,在该层可观察到严重的微胞饮作用。在肺泡上皮ABB层观察到明显的破坏变化,直至肺泡腔内出现细胞内容物,上皮基底膜剥脱。

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