Ozirskaia E V
Tsitologiia. 1977;19(1):28-32.
The ultrastructure of the blood-air barrier in rabbits was investigated during different periods after i. v. injection of high hydrophobic organophosphorus cholinesterase inhibitor GA-95. According to the biochemical data, this inhibitor is accumulated mostly in the lungs. The most pronounced changes observed 20 min after injection involved a significant increase in number of pinocytose vesicles in the cytoplasm of endothelial cells of lung capillaries. The morphological data may serve an indirect evidence for the inhibitor sorption at the surface of lung capillaries.
在静脉注射高疏水性有机磷胆碱酯酶抑制剂GA - 95后的不同时期，对家兔气血屏障的超微结构进行了研究。根据生化数据，这种抑制剂主要在肺部蓄积。注射后20分钟观察到的最明显变化是肺毛细血管内皮细胞质中胞饮小泡数量显著增加。这些形态学数据可作为抑制剂在肺毛细血管表面吸附的间接证据。
