Grant A. Pignatiello is an instructor and KL2 Clinical Research Scholar, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio.
Aloen L. Townsend is the Ralph S. and Dorothy P. Schmitt Professor of Social Work, Jack, Joseph, and Morton Mandel School of Applied Social Sciences, Case Western Reserve University.
Am J Crit Care. 2021 May 1;30(3):212-220. doi: 10.4037/ajcc2021214.
The Hospital Anxiety and Depression Scale (HADS) is commonly used clinically and scientifically among surrogate decision makers for critically ill patients. The validity of the HADS has been scrutinized, but its use among surrogate decision makers has not been examined.
To examine the structural validity of the HADS.
This study was a secondary analysis of data obtained from a 3-arm randomized controlled trial of a decision support intervention. Participants were recruited from 6 intensive care units at a tertiary medical center in Northeast Ohio. Participants were adult surrogate decision makers for critically ill, cognitively impaired adults who were not expected to be discharged from the intensive care unit within the subsequent 48 hours. The fit of 2-factor, 3-factor, and bifactor structures of the HADS was tested with confirmatory factor analysis.
The bifactor structure, possessing a general psychological distress factor and anxiety and depression group factors, showed a superior fit and met a priori thresholds for acceptable model fit. The general psychological distress factor accounted for more than 75% of the common variance in the HADS items.
Confirmatory factor analysis provided evidence supporting a bifactor structure of the HADS. In this sample, the instrument validly measures psychological distress rather than distinct symptoms of anxiety and depression. Replication of these results is encouraged, and use of alternative measures is recommended when measuring distinct symptoms of anxiety and depression among surrogate decision makers for critically ill patients.
在重症患者的替代决策人临床和科研中,常使用医院焦虑抑郁量表(HADS)。HADS 的有效性已受到详细审查,但尚未对替代决策人使用 HADS 的情况进行检验。
检验 HADS 的结构有效性。
本研究是对来自俄亥俄州东北部一家三级医疗中心 6 个重症监护病房的一项决策支持干预措施的 3 臂随机对照试验数据的二次分析。参与者为重症、认知障碍且预计在接下来 48 小时内不能从重症监护病房出院的成年患者的替代决策人。采用验证性因子分析检验 HADS 的 2 因素、3 因素和双因素结构的拟合度。
双因素结构,具有一般心理困扰因素和焦虑与抑郁组因素,具有更好的拟合度,且符合可接受模型拟合的先验标准。一般心理困扰因素占 HADS 项目共同方差的 75%以上。
验证性因子分析为 HADS 的双因素结构提供了证据支持。在该样本中,该工具可有效测量心理困扰,而不是焦虑和抑郁的特定症状。鼓励对这些结果进行复制,并建议在测量重症患者替代决策人焦虑和抑郁的特定症状时使用替代测量方法。