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新冠疫情封锁对意大利国民医疗服务体系的经济影响:聚焦糖尿病

Economic Impact of COVID-19 Lockdown on Italian NHS: Focus on Diabetes Mellitus.

作者信息

Torre Enrico, Colombo Giorgio Lorenzo, Di Matteo Sergio, Martinotti Chiara, Valentino Maria Chiara, Rebora Alberto, Cecoli Francesca, Monti Eleonora, Galimberti Marco, Di Bartolo Paolo, Gaggioli Germano, Bruno Giacomo Matteo

机构信息

Endocrinology Diabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.

Department of Drug Sciences, University of Pavia, Pavia, Italy.

出版信息

Clinicoecon Outcomes Res. 2021 Jun 14;13:503-518. doi: 10.2147/CEOR.S313577. eCollection 2021.

Abstract

BACKGROUND

In Italy, the adoption of a total lockdown has generated almost total suspension of outpatient visits except for emergencies. Even after lockdown, the pandemic fear created additional barriers to access the health services. The aim of our study is to evaluate the economic impact of the lockdown for COVID-19 on public health in Italy, focusing on its effects on diabetic population.

MATERIALS AND METHODS

We analyzed the impact of the lockdown on excess mortality and morbidity in the Italian diabetic population during 2020. The analysis was divided into several steps: a quantification of specialist visit reduction, the calculation of excess mortality in the diabetic population, the economic evaluation of the slowdown in the use of innovative diabetic therapies. Furthermore, the impact of the lockdown on the reduction of procedures and follow-up visits in diabetic population was evaluated. The overall impact of the pandemic and lockdown effects on costs and quality of life was then calculated.

RESULTS

During 2020, a drop of 28% in patient access has been observed. Diabetic patients recorded a twice higher mortality value compared to general population (20.4% vs 10.2%). The analysis of market data revealed a slowdown in consumption of new antidiabetic therapies (-14%, 27% vs 41%). We estimated an expense of €26.6 million for NHS and a loss of 257 utilities in diabetic population due to the missed benefits related to slowdown in innovative antidiabetic drugs use and non-optimal follow-up and control of diabetes complications. In simulation scenarios, we also estimated an overall expenditure ranging from €38.7 to 94.0 million and a loss of 294-836 utilities.

CONCLUSION

Diabetic population paid a high tribute to pandemic and lockdown, both in terms of number of deaths and burden of diabetic complications, together with an overall deterioration of quality of life.

摘要

背景

在意大利,全面封锁几乎导致除急诊外的门诊就诊全面暂停。即使在封锁解除后,对疫情的恐惧也给获得医疗服务带来了额外障碍。我们研究的目的是评估意大利因新冠疫情封锁对公共卫生产生的经济影响,重点关注其对糖尿病患者群体的影响。

材料与方法

我们分析了2020年封锁对意大利糖尿病患者群体超额死亡率和发病率的影响。分析分为几个步骤:量化专科就诊减少情况、计算糖尿病患者群体的超额死亡率、对创新糖尿病治疗使用放缓进行经济评估。此外,还评估了封锁对糖尿病患者群体手术和随访就诊减少的影响。然后计算了疫情和封锁影响对成本和生活质量的总体影响。

结果

2020年期间,患者就诊量下降了28%。糖尿病患者的死亡率是普通人群的两倍(20.4%对10.2%)。对市场数据的分析显示新型抗糖尿病治疗的消费量有所放缓(-14%,27%对41%)。由于创新抗糖尿病药物使用放缓以及糖尿病并发症的随访和控制不理想导致的益处缺失,我们估计国民健康服务体系支出2660万欧元,糖尿病患者群体损失257个效用值。在模拟情景中,我们还估计总支出在3870万至9400万欧元之间,损失294 - 836个效用值。

结论

糖尿病患者群体在死亡人数、糖尿病并发症负担以及生活质量全面恶化方面都为疫情和封锁付出了高昂代价。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cf1/8213950/1eb8e78091e2/CEOR-13-503-g0001.jpg

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