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西德纳姆舞蹈病:临床、脑电图、CT扫描及诱发电位研究。

Sydenham's chorea: clinical, EEG, CT scan, and evoked potential studies.

作者信息

Ganji S, Duncan M C, Frazier E

机构信息

Department of Neurology, Louisiana State University School of Medicine, New Orleans 70112.

出版信息

Clin Electroencephalogr. 1988 Jul;19(3):114-22. doi: 10.1177/155005948801900304.

DOI:10.1177/155005948801900304
PMID:3416495
Abstract

An 8-year-old child developed acute mental confusion, and choreoathetosis without a preceding history of acute rheumatic fever. Serial EEGs showed focal suppression of sleep spindle activity over the right cerebral hemisphere along with high-amplitude polymorphic slow-wave complexes. CT scan studies on 4 occasions and MRI scan failed to show focal lesions corresponding to the clinical manifestations. Results of brainstem auditory evoked potential studies were normal. The short- and long-latency somatosensory evoked potential patterns were abnormal during the acute phase of illness as well as during the follow-up, when the patient was clinically intact. The persistent EEG and evoked potential abnormalities in the presence of clinical recovery from chorea raised questions as to the existence of a subclinical disease process.

摘要

一名8岁儿童出现急性精神错乱和舞蹈徐动症,之前并无急性风湿热病史。系列脑电图显示右大脑半球睡眠纺锤波活动局灶性抑制,伴有高波幅多形性慢波复合波。4次CT扫描研究及MRI扫描均未显示与临床表现相对应的局灶性病变。脑干听觉诱发电位研究结果正常。在疾病急性期以及随访期间(此时患者临床症状已恢复),短潜伏期和长潜伏期体感诱发电位模式均异常。舞蹈症临床症状恢复但脑电图和诱发电位持续异常,这引发了关于是否存在亚临床疾病过程的疑问。

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引用本文的文献

1
Sydenham chorea: clinical, EEG, MRI and SPECT findings in the early stage of the disease.
J Neurol. 1993 Feb;240(2):121-3. doi: 10.1007/BF00858729.
2
Standard neurodiagnostic tests in Sydenham's chorea.风湿性舞蹈病的标准神经诊断测试。
J Neurol Neurosurg Psychiatry. 1990 Jun;53(6):534-5. doi: 10.1136/jnnp.53.6.534-a.