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西德纳姆舞蹈病与癫痫发作。临床及脑电图研究。

Sydenham's chorea and seizures. Clinical and electroencephalographic studies.

作者信息

Ch'ien L T, Economides A N, Lemmi H

出版信息

Arch Neurol. 1978 Jun;35(6):382-5. doi: 10.1001/archneur.1978.00500300056010.

DOI:10.1001/archneur.1978.00500300056010
PMID:655913
Abstract

The hospital records of 28 children (mean age, 9.4 years) with typical Sydenham's chorea were reviewed. Nineteen of 28 patients had antistreptolysin O titers of greater than or equal to 200 Todd units. Other causes of chorea were excluded by appropriate laboratory and clinical follow-up studies. At the onset of the movement disorder, 17 of 28 patients had abnormal EEGs consisting of irregular posterior slowing in 15, sharp epileptic spikes in 5, and high-voltage sharp waves in 2. Two patients with spikes predominantly in the temporal lobe regions developed complex partial seizures. On follow-up evaluation, the EEGs returned to normal within one to four weeks. Seizures did not recur after therapy with anticonvulsants. Seizures have been reported only rarely in association with Sydenham's chorea. Our observation suggests that seizures may occur during chorea but may often be masked by frequent choreic movements and thus not recognized. The EEG changes and seizures were transient in our patients studied so far.

摘要

回顾了28例(平均年龄9.4岁)典型小舞蹈病患儿的医院记录。28例患者中有19例抗链球菌溶血素O滴度大于或等于200托德单位。通过适当的实验室和临床随访研究排除了其他舞蹈病病因。在运动障碍发作时,28例患者中有17例脑电图异常,其中15例表现为不规则的后部慢波,5例出现尖锐癫痫波,2例出现高电压锐波。2例主要在颞叶区域出现尖波的患者发生了复杂部分性发作。在随访评估中,脑电图在1至4周内恢复正常。抗惊厥药物治疗后癫痫未复发。与小舞蹈病相关的癫痫报道很少。我们的观察表明,癫痫可能在舞蹈病期间发生,但常被频繁的舞蹈样动作掩盖而未被识别。在我们目前研究的患者中,脑电图改变和癫痫都是短暂的。

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Glob Heart. 2022 Aug 29;17(1):62. doi: 10.5334/gh.1149. eCollection 2022.
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Language Impairment in Adolescents with Sydenham Chorea.患有 Sydenham 舞蹈病青少年的语言障碍
Pediatr Neurol Briefs. 2015 Nov;29(11):87. doi: 10.15844/pedneurbriefs-29-11-6.
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Standard neurodiagnostic tests in Sydenham's chorea.风湿性舞蹈病的标准神经诊断测试。
J Neurol Neurosurg Psychiatry. 1990 Jun;53(6):534-5. doi: 10.1136/jnnp.53.6.534-a.