Pongpanich B, Daengroongroj P
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Clin Rheumatol. 1988 Jun;7(2):257-61. doi: 10.1007/BF02204464.
The clinical characteristic of 100 patients diagnosed for JRA at the Department of Pediatrics, Ramathibodi Hospital, Bangkok, Thailand during 1968-1984 are reported. There were 64 male and 36 female patients with a respective ratio of 1.7:1. In ninety-one percent the age of onset was over the age of five, the most common type being polyarticular onset (77%) followed by pauciarticular onset (13%) and systemic onset (10%). Twenty percent had a positive rheumatoid factor and 4% had cardiac complications. Over half of the patients (58%) responded to salicylate and other supportive treatment. The overall remission was 36 percent with a mean follow-up of 3.8 years. The highest remission rate was found in the polyarticular type of onset (43%) followed by systemic onset (33%) and pauciarticular onset (23%). Only 11 percent of the patients responded poorly to the treatment. As opposed to Western reports differences occurred in the type of onset, sex, and eye complications.
本文报告了1968年至1984年期间在泰国曼谷拉玛提波迪医院儿科诊断为幼年类风湿性关节炎(JRA)的100例患者的临床特征。其中男性患者64例,女性患者36例,男女比例为1.7:1。91%的患者发病年龄超过5岁,最常见的类型是多关节起病(77%),其次是少关节起病(13%)和全身起病(10%)。20%的患者类风湿因子呈阳性,4%的患者有心脏并发症。超过一半的患者(58%)对水杨酸盐和其他支持性治疗有反应。总体缓解率为36%,平均随访时间为3.8年。缓解率最高的是多关节起病类型(43%),其次是全身起病(33%)和少关节起病(23%)。只有11%的患者对治疗反应不佳。与西方报告不同的是,在起病类型、性别和眼部并发症方面存在差异。