Kobayashi T, Tanaka S, Maeda M, Okubo H, Matsuyama T, Watanabe N
Department of Pediatrics, Kyorin University School of Medicine, Tokyo, Japan.
Acta Paediatr Jpn. 1993 Oct;35(5):439-46. doi: 10.1111/j.1442-200x.1993.tb03088.x.
The prognosis in 52 patients with juvenile rheumatoid arthritis (JRA) was studied. There were 35 cases of systemic onset, 12 of polyarticular onset and 5 of pauciarticular onset. Thirteen systemic cases developed a polycyclic course with chronic polyarthritis. Many monocyclic JRA in systemic cases subsided within 1 year. There were no instances of polyarticular cases or pauciarticular cases that shifted to other type. However, there were many cases with a long active polyarticular JRA and with remission at an early stage in the pauciarticular type. The stage and class were I or II in 90% of cases with a good prognosis for the joints, but there were some serious cases. Transient carditis or iritis which developed at an early stage subsided later. The intractable systemic cases had drug-induced complications. The cases with steroid-induced complications tended to be chronic. One death in a systemic case was caused by hepatic failure.
对52例青少年类风湿性关节炎（JRA）患者的预后进行了研究。全身型发病35例，多关节型发病12例，少关节型发病5例。13例全身型病例发展为慢性多关节炎的多循环病程。全身型病例中的许多单循环JRA在1年内消退。多关节型病例或少关节型病例均无转变为其他类型的情况。然而，多关节型JRA活动期长的病例以及少关节型早期缓解的病例较多。90%关节预后良好的病例分期和分级为I或II级，但也有一些严重病例。早期出现的短暂性心脏炎或虹膜炎后来消退。难治性全身型病例有药物引起的并发症。类固醇引起并发症的病例往往呈慢性。1例全身型病例死亡由肝衰竭所致。
