• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

《健康专业学员的抗-HBs 效价：意大利中部一所大学的抗体保护率》

"Titer of anti-HBs in health professions trainees: prevalence of antibody coverage in a University of Central Italy".

机构信息

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University, Chieti, Italy.

Department of Economic Studies, University G. d'Annunzio Chieti-Pescara, Pescara, Italy.

出版信息

Hum Vaccin Immunother. 2022 Dec 31;18(1):1886805. doi: 10.1080/21645515.2021.1886805. Epub 2021 Jun 24.

DOI:10.1080/21645515.2021.1886805
PMID:34166177
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8942411/
Abstract

OBJECTIVE

This observational retrospective study aims at verifying hepatitis-B-virus (HBV) vaccination coverage in students vaccinated before and after 1992, in order to optimize health surveillance and vaccination recall.

METHODS

Vaccination status was evaluated using the anti-HBs antibody titer (anti-HBs). Student t-test and the chi-square test were performed to identify the average age and the difference in antibody coverage between the two genders and in the two populations analyzed.

RESULTS

Our study outlined a prevalence of 21.83% uncovered trainees among those vaccinated at age 12 and 45.03% among those vaccinated in neonatal age.

CONCLUSION

In conclusion, our data showed persistent protection against HBV infection in healthcare students.

摘要

目的

本观察性回顾性研究旨在验证 1992 年前后接种乙型肝炎病毒（HBV）疫苗的学生的疫苗接种率，以优化健康监测和疫苗接种召回。

方法

使用抗-HBs 抗体滴度（抗-HBs）评估疫苗接种状态。采用学生 t 检验和卡方检验比较两种人群中男女之间及两种疫苗接种年龄组之间的平均年龄和抗体覆盖率差异。

结果

本研究发现，12 岁时接种疫苗的人群中有 21.83%未接种疫苗，而新生儿时期接种疫苗的人群中有 45.03%未接种疫苗。

结论

综上所述，我们的数据表明，医疗保健专业学生对 HBV 感染具有持续的保护作用。

相似文献

1
"Titer of anti-HBs in health professions trainees: prevalence of antibody coverage in a University of Central Italy".《健康专业学员的抗-HBs 效价：意大利中部一所大学的抗体保护率》
Hum Vaccin Immunother. 2022 Dec 31;18(1):1886805. doi: 10.1080/21645515.2021.1886805. Epub 2021 Jun 24.
2
Is hepatitis B vaccination performed at infant and adolescent age able to provide long-term immunological memory? An observational study on healthcare students and workers in Florence, Italy.在婴幼儿时期进行乙型肝炎疫苗接种是否能够提供长期的免疫记忆？一项针对意大利佛罗伦萨医护学生和工作人员的观察性研究。
Hum Vaccin Immunother. 2018 Feb 1;14(2):450-455. doi: 10.1080/21645515.2017.1398297. Epub 2017 Dec 19.
3
Significance and anamnestic response in isolated hepatitis B core antibody-positive individuals 18 years after neonatal hepatitis B virus vaccination in Taiwan.台湾地区新生儿乙型肝炎病毒疫苗接种 18 年后，单纯乙型肝炎核心抗体阳性个体的意义和既往反应。
Vaccine. 2012 Jun 8;30(27):4034-9. doi: 10.1016/j.vaccine.2012.04.031. Epub 2012 Apr 22.
4
Persistence of Immunity for Hepatitis B Virus among Heathcare Workers and Italian Medical Students 20 Years after Vaccination.乙型肝炎病毒免疫持久性：接种疫苗 20 年后医护人员和意大利医学生的情况
Int J Environ Res Public Health. 2019 Apr 29;16(9):1515. doi: 10.3390/ijerph16091515.
5
The long-term immunogenicity of recombinant hepatitis B virus (HBV) vaccine: contribution of universal HBV vaccination in Italy.重组乙型肝炎病毒（HBV）疫苗的长期免疫原性：意大利普遍接种HBV疫苗的作用。
BMC Infect Dis. 2015 Mar 25;15:149. doi: 10.1186/s12879-015-0874-3.
6
Long-term immune protection against HBV: associated factors and determinants.长期的乙型肝炎病毒免疫保护：相关因素和决定因素。
Hum Vaccin Immunother. 2021 Jul 3;17(7):2268-2272. doi: 10.1080/21645515.2020.1852869. Epub 2021 Jan 31.
7
Hepatitis B surface antibodies in medical students from a public university in Puebla, Mexico.墨西哥普埃布拉一所公立大学医学生的乙肝表面抗体
Hum Vaccin Immunother. 2016 Jul 2;12(7):1857-62. doi: 10.1080/21645515.2016.1151587. Epub 2016 May 12.
8
Prevalence of hepatitis B virus infection among health care workers in a tertiary hospital in Tanzania.坦桑尼亚一家三级医院医护人员中乙肝病毒感染的患病率
BMC Infect Dis. 2015 Sep 23;15:386. doi: 10.1186/s12879-015-1129-z.
9
Hepatitis B virus vaccination booster does not provide additional protection in adolescents: a cross-sectional school-based study.乙肝疫苗加强针不能为青少年提供额外保护：一项基于学校的横断面研究。
BMC Public Health. 2014 Sep 23;14:991. doi: 10.1186/1471-2458-14-991.
10
Immunogenicity of compulsory and booster doses of hepatitis B vaccine among children in Cairo, Egypt.埃及开罗儿童中乙肝疫苗强制接种剂量和加强剂量的免疫原性。
J Egypt Public Health Assoc. 2017 Jun 1;92(2):77-85. doi: 10.21608/epx.2018.8945.

引用本文的文献

1
Persistence of Anti-HB Antibodies in Healthcare Trainees: The Impact of Childhood Versus Adolescent Vaccination.医疗培训人员中抗-HB抗体的持续性：儿童期与青春期疫苗接种的影响
Vaccines (Basel). 2025 May 26;13(6):562. doi: 10.3390/vaccines13060562.
2
Impact of the Hepatitis B Immunization Strategy Adopted in Italy from 1991: The Results of a Seroprevalence Study on the Adult Population of Florence, Italy.1991年起意大利采用的乙肝免疫策略的影响：意大利佛罗伦萨成年人群血清流行率研究结果
Pathogens. 2025 Apr 7;14(4):362. doi: 10.3390/pathogens14040362.
3
Factors influencing the utilisation of anti-HBs titre testing services among nursing students in Northwest Ghana: A cross-sectional study.加纳西北部护理专业学生抗-HBs 滴度检测服务利用情况的影响因素：一项横断面研究。
PLOS Glob Public Health. 2024 Apr 25;4(4):e0003160. doi: 10.1371/journal.pgph.0003160. eCollection 2024.
4
Epidemiology of Chronic Hepatitis B Infection in the Cohort of College Students with Vaccination in Taiwan.台湾大学生接种疫苗队列中慢性乙型肝炎感染的流行病学
Vaccines (Basel). 2023 Feb 3;11(2):348. doi: 10.3390/vaccines11020348.
5
Long-Term Effectiveness of Hepatitis B Vaccination in the Protection of Healthcare Students in Highly Developed Countries: A Systematic Review and Meta-Analysis.乙肝疫苗接种对高度发达国家医护专业学生的长期保护效果：一项系统评价与荟萃分析
Vaccines (Basel). 2022 Oct 30;10(11):1841. doi: 10.3390/vaccines10111841.
6
Night Shift Work Is Associated with Reduced Rate of Humoral Response Following Vaccination for HBV.夜班工作与乙肝疫苗接种后体液免疫反应率降低有关。
Int J Environ Res Public Health. 2022 Jul 20;19(14):8834. doi: 10.3390/ijerph19148834.

本文引用的文献

1
Immune persistence 17 to 20 years after primary vaccination with recombination hepatitis B vaccine (CHO) and the effect of booster dose vaccination.初免重组乙型肝炎疫苗（CHO）后 17 至 20 年的免疫持久性和加强免疫接种的效果。
BMC Infect Dis. 2019 May 30;19(1):482. doi: 10.1186/s12879-019-4134-9.
2
What is changed in HBV molecular epidemiology in Italy?意大利的 HBV 分子流行病学有哪些变化？
J Med Virol. 2018 May;90(5):786-795. doi: 10.1002/jmv.25027. Epub 2018 Feb 5.
3
Effects of hepatitis B vaccine boosters on anti-HBs-negative children after primary immunization.乙肝疫苗加强免疫对初次免疫后抗-HBs阴性儿童的影响。
Hum Vaccin Immunother. 2017 Apr 3;13(4):903-908. doi: 10.1080/21645515.2016.1260794. Epub 2016 Dec 1.
4
Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose.乙肝疫苗接种后的抗体水平与保护作用：一项30年随访研究的结果及对加强剂量的反应
J Infect Dis. 2016 Jul 1;214(1):16-22. doi: 10.1093/infdis/jiv748. Epub 2016 Jan 21.
5
Prevention and Management of Chronic Hepatitis B.慢性乙型肝炎的预防与管理
Int J Prev Med. 2014 Dec;5(Suppl 3):S200-7.
6
Vaccination against hepatitis b virus: are Italian medical students sufficiently protected after the public vaccination programme?乙型肝炎病毒疫苗接种：在公共疫苗接种计划之后，意大利医科学生是否得到了充分的保护？
J Occup Med Toxicol. 2015 Nov 4;10:41. doi: 10.1186/s12995-015-0083-4. eCollection 2015.
7
Vaccination of healthcare workers: A review.医护人员的疫苗接种：综述
Hum Vaccin Immunother. 2015;11(11):2522-37. doi: 10.1080/21645515.2015.1082014.
8
Prevention of hepatitis B.乙型肝炎的预防
Cold Spring Harb Perspect Med. 2015 Mar 2;5(3):a021493. doi: 10.1101/cshperspect.a021493.
9
Epidemiology of acute and chronic hepatitis B and delta over the last 5 decades in Italy.意大利过去50年中急性和慢性乙型肝炎及丁型肝炎的流行病学。
World J Gastroenterol. 2014 Jun 28;20(24):7635-43. doi: 10.3748/wjg.v20.i24.7635.
10
Antibody persistence and the effect of a booster dose given 5, 10 or 15 years after vaccinating preadolescents with a recombinant hepatitis B vaccine.抗体持久性以及在给青春期前儿童接种重组乙型肝炎疫苗 5、10 或 15 年后加强剂量的效果。
Vaccine. 2013 Jan 7;31(3):448-51. doi: 10.1016/j.vaccine.2012.11.037. Epub 2012 Dec 1.