Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, USA.
Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.
Lancet. 2021 Jul 10;398(10295):171-184. doi: 10.1016/S0140-6736(21)00233-6. Epub 2021 Jun 21.
Oncology care is increasingly a multidisciplinary endeavour, and radiation therapy continues to have a key role across the disease spectrum in nearly every cancer. However, the field of radiation oncology is still one of the most poorly understood of the cancer disciplines. In this Review, we attempt to summarise and contextualise developments within the field of radiation oncology for the non-radiation oncologist. We discuss advancements in treatment technologies and imaging, followed by an overview of the interplay with advancements in systemic therapy and surgical techniques. Finally, we review new frontiers in radiation oncology, including advances within the metastatic disease continuum, reirradiation, and emerging types of radiation therapy.
肿瘤学治疗越来越倾向于多学科联合治疗,而放射治疗在几乎所有癌症的疾病谱中都继续发挥着关键作用。然而,放射肿瘤学领域仍然是癌症学科中最不被理解的领域之一。在这篇综述中,我们试图为非放射肿瘤学家总结和阐述放射肿瘤学领域的发展。我们讨论了治疗技术和成像方面的进展,接着概述了与系统治疗和手术技术进步的相互作用。最后,我们回顾了放射肿瘤学的新前沿,包括转移性疾病连续体、再放射治疗和新兴类型的放射治疗方面的进展。