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用于放射治疗直线加速器中热中子探测的碳化硅P-N二极管的评估。

Evaluation of a silicon carbide P-N diode for thermal neutron detection in a radiotherapy LINAC.

作者信息

Pérez Martín, Zamorano Felipe, Fleta Celeste, Muñoz-Montplet Carles, Jurado-Bruggeman Diego, Jiménez Marcio, Guardia Pablo, Grabulosa-Morera Gina, Morales-Pérez Roger, Rius Gemma, Godignon Philippe, Pellegrini Giulio, Guardiola Consuelo

机构信息

Institute of Microelectronics of Barcelona (IMB-CNM-CSIC), 08193, Cerdanyola del Vallés (Bellaterra), Spain.

Medical Physics and Radiation Protection Department, Catalan Institute of Oncology (ICO), 17007, Girona, Spain.

出版信息

Sci Rep. 2025 Aug 20;15(1):30543. doi: 10.1038/s41598-025-13052-w.

DOI:10.1038/s41598-025-13052-w
PMID:40835631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12368008/
Abstract

Accurate neutron detection in mixed photon-neutron and pulsed radiation fields is technically challenging, impacting industrial and medical applications. This paper presents the first measurements of thermal neutrons in conventional radiotherapy accelerators using a silicon carbide (SiC) P-N diode with different neutron converters. SiC detectors enable real-time estimation of secondary thermal neutron contributions, crucial for emerging radiotherapy techniques requiring precise neutron fluence monitoring. Beyond medical applications, the presented detectors show potential for neutron dosimetry, radiation monitoring, nuclear safety, and scientific research. The SiC diode active detection layer is less than 30 µm thick, and provides excellent gamma rejection ([Formula: see text]), allowing discrimination of neutrons-induced events in mixed radiation fields. Experimental tests conducted on a TrueBeam radiotherapy LINAC demonstrated a thermal neutron detection efficiency of (4.32 ± 0.02)% for a (50 ± 10) µm thick [Formula: see text]LiF neutron converter. The detector, placed at 1.2 m from the accelerator isocenter, was used to measure neutron fluences at different monitor unit (MU) rates, ranging from 100 to 600 MU/min, with the LINAC operating at 15 MV. Under these conditions, the detector exhibited good linearity, without saturation or dead time effects.

摘要

在混合光子 - 中子和脉冲辐射场中进行精确的中子探测在技术上具有挑战性,这影响了工业和医疗应用。本文首次使用带有不同中子转换器的碳化硅(SiC)P - N二极管对传统放射治疗加速器中的热中子进行了测量。SiC探测器能够实时估计二次热中子的贡献,这对于需要精确中子注量监测的新兴放射治疗技术至关重要。除了医疗应用外,所展示的探测器在中子剂量测定、辐射监测、核安全和科学研究方面也具有潜力。SiC二极管有源探测层厚度小于30 µm,并具有出色的γ射线抑制能力([公式:见原文]),能够在混合辐射场中区分中子诱发的事件。在TrueBeam放射治疗直线加速器上进行的实验测试表明,对于厚度为(50 ± 10)µm的[公式:见原文]LiF中子转换器,热中子探测效率为(4.32 ± 0.02)%。该探测器放置在距加速器等中心1.2 m处,用于测量直线加速器在15 MV运行时,不同监测单位(MU)速率(范围为100至600 MU/min)下的中子注量。在这些条件下,探测器表现出良好的线性,没有饱和或死时间效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/94e6282c7300/41598_2025_13052_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/6717b50d3ffc/41598_2025_13052_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f311c91eba2c/41598_2025_13052_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f2391a6f0894/41598_2025_13052_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f118bae77244/41598_2025_13052_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/94e6282c7300/41598_2025_13052_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/6717b50d3ffc/41598_2025_13052_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/a51cc83dbc70/41598_2025_13052_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/15bfa69bbf13/41598_2025_13052_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/d181176ca071/41598_2025_13052_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f311c91eba2c/41598_2025_13052_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f2391a6f0894/41598_2025_13052_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/f118bae77244/41598_2025_13052_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e492/12368008/94e6282c7300/41598_2025_13052_Fig8_HTML.jpg

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本文引用的文献

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2
Out-of-field neutron radiation from clinical proton, helium, carbon, and oxygen ion beams.临床质子、氦离子、碳离子和氧离子束的野外中子辐射。
Med Phys. 2025 Jun;52(6):4924-4940. doi: 10.1002/mp.17797. Epub 2025 Apr 4.
3
Simulating the head of a TrueBeam linear particle accelerator and calculating the photoneutron spectrum on the central axis of a 10-MV photon using particle and heavy-ion transport system code.
使用粒子与重离子传输系统代码模拟TrueBeam直线加速器的头部,并计算10兆伏光子中心轴上的光中子能谱。
Radiat Prot Dosimetry. 2024 Jun 3;200(8):779-790. doi: 10.1093/rpd/ncae124.
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State-of-the-art silicon carbide diode dosimeters for ultra-high dose-per-pulse radiation at FLASH radiotherapy.用于 FLASH 放射治疗中超高脉冲剂量辐射的最先进碳化硅二极管剂量计。
Phys Med Biol. 2024 Apr 19;69(9). doi: 10.1088/1361-6560/ad37eb.
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First use of silicon carbide detectors with graphene-enhanced contacts for medical dosimetry.首次将具有石墨烯增强型触点的碳化硅探测器用于医学剂量测定。
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