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维生素 D 水平低作为良性阵发性位置性眩晕(BPPV)复发的协同因子的作用。

The role of low levels of vitamin D as a co-factor in the relapse of benign paroxysmal positional vertigo (BPPV).

机构信息

Audiovestibular Medicine Unit, ENT Department, Al-Azhar University, Assiut, Egypt.

Rheumatology and Rehabilitation Department, Al-Azhar University, Assiut, Egypt.

出版信息

Am J Otolaryngol. 2021 Nov-Dec;42(6):103134. doi: 10.1016/j.amjoto.2021.103134. Epub 2021 Jun 19.

DOI:10.1016/j.amjoto.2021.103134
PMID:34166965
Abstract

BACKGROUND

Benign paroxysmal positional vertigo is characterized as brief episodes of vertigo that are exacerbated by the unexpected act of moving to a current provoking location. It is thought to be an otoconia-related balance disorder. Our objectives were to assess the serum concentrations of vitamin D and calcium (total and ionized) in cases with BPPV, determine if low vitamin D levels were regarded as a cause for BPPV relapse, and determine whether vitamin D supplementation would minimize the risk of BPPV relapse.

RESULTS

Sixty cases with BPPV were included in the study; 53 cases had posterior canal BPPV, while seven had lateral canal BPPV. Canalithiasis was the most common type of BPPV pathology. Forty cases had abnormally low levels of vitamin D. There was a statistically significant positive correlation between the mean vitamin D assay for all cases with BPPV and serum calcium. There was statistically significant difference in comparing the relapse of BPPV for group that receive vitamin D after one year follow up.

CONCLUSION

Abnormal vitamin D levels were linked with the incident and relapse of BPPV. Correction of low vitamin D levels was linked with the reduction of the relapse of BPPV.

摘要

背景

良性阵发性位置性眩晕的特征是短暂的眩晕发作,这些发作会因突然移动到当前诱发位置而加剧。它被认为是一种与耳石相关的平衡障碍。我们的目的是评估患有 BPPV 的患者的血清维生素 D 和钙(总钙和离子钙)浓度,确定低维生素 D 水平是否被认为是 BPPV 复发的原因,以及确定维生素 D 补充是否会降低 BPPV 复发的风险。

结果

本研究纳入了 60 例 BPPV 患者;53 例为后管 BPPV,7 例为侧管 BPPV。耳石症是 BPPV 最常见的病理类型。40 例患者维生素 D 水平异常降低。所有 BPPV 患者的平均维生素 D 检测值与血清钙之间存在显著正相关。在接受维生素 D 治疗一年后的随访中,BPPV 复发的两组之间存在统计学显著差异。

结论

异常的维生素 D 水平与 BPPV 的发生和复发有关。纠正低维生素 D 水平与降低 BPPV 复发有关。

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