Gastrin/CCK-like immunoreactivity in Hatschek's groove of Branchiostoma lanceolatum (Cephalochordata).

Gastrin/CCK-like immunoreactivity was demonstrated in a specific group of epithelial cells in Hatschek's groove. Positive reactions were obtained with antisera directed against the C-terminal amino acid sequence common to mammalian CCK and gastrin, but not with antisera against the midportions of these hormones. No immunoreactivity was obtained with antisera against peptides from hypophysis, neuroendocrine peptides in the gastrointestinal tract, islet hormones, calcitonin, NSE, and S-100. The function of the gastrin/CCK-like peptide found in Hatschek's groove is discussed.