左旋咪唑——肥胖带绦虫小鼠实验系统中的生物反应调节剂。
Levamisole--biological response modifier in Taenia crassiceps--mouse experimental system.
作者信息
Lukes S
机构信息
Institute of Parasitology, Czechoslovak Academy of Sciences, Ceské Budĕjovice.
出版信息
Folia Parasitol (Praha). 1988;35(1):37-40.
PMID:3417199
Abstract
Levamisole, a common anthelminthic preparation, was used for the modification of the immune response of mice to vaccination with soluble antigen from Taenia crassiceps. The combination of antigen with Levamisole significantly increased the immunogenic effect of the antigen. Metacestodes survived in 16.7% after one dose and in 42.9% after two doses of Levamisole. The percentage of resistance was 97.7% and 67.8%.
摘要
左旋咪唑是一种常见的驱虫制剂，被用于改变小鼠对来自粗颈绦虫可溶性抗原疫苗接种的免疫反应。抗原与左旋咪唑的组合显著提高了抗原的免疫原性效果。一剂左旋咪唑后，囊尾蚴的存活率为16.7%，两剂后为42.9%。抗性百分比分别为97.7%和67.8%。
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