Esophageal and Airway Treatment Center, Department of Pediatric General Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Esophageal and Airway Treatment Center, Department of Pediatric General Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Semin Pediatr Surg. 2021 Jun;30(3):151062. doi: 10.1016/j.sempedsurg.2021.151062. Epub 2021 May 23.
Airway collapse from dynamic tracheobronchomalacia (TBM), static compression from vascular compression, and/or tracheobronchial deformation are challenging conditions. Patients are best assessed and managed by a multidisciplinary team in centers specializing in complex pediatric airway disorders. Suspicion is made through clinical history and physical examination, diagnosis of location and severity by dynamic 3-phase bronchoscopy, and surgical treatment planning by MDCT and other studies as necessary to completely understand the problems. The treatment plan should be patient-based with a thorough approach to the underlying pathology, clinical concerns, and combined abnormalities. Patients should undergo maximum medical therapy prior to committing to other interventions. For those children considered candidates for surgical intervention, all other associated conditions, including vascular anomalies, chest wall deformities, mediastinal lesions, or other airway pathologies, should also be considered. Our preference is to correct the airway lesions at the same operation as other comorbidities, if possible, to prevent multiple reoperations with their attendant increased risks. We also strongly advocate for the use of recurrent laryngeal nerve monitoring in all cases of cervical or thoracic surgery to minimize the risks to vocal cord function and laryngeal sensation. Studies that evaluate the effect of these interventions on the patient and caregiver's quality of life are needed to fully grasp the impact of TBM on this challenging patient population.
气道塌陷可由动态性气管支气管软化(TBM)、血管压迫引起的静态压迫和/或气管支气管变形引起,这些都是具有挑战性的情况。通过多学科团队在专门治疗复杂儿科气道疾病的中心,对患者进行最佳评估和管理。通过临床病史和体格检查怀疑存在该疾病,通过动态 3 相支气管镜检查诊断位置和严重程度,必要时通过 MDCT 和其他研究进行手术治疗计划,以全面了解问题。治疗计划应基于患者,并对潜在病理学、临床关注点和合并异常进行彻底的处理。在承诺进行其他干预之前,患者应接受最大程度的药物治疗。对于那些被认为适合手术干预的儿童,所有其他相关疾病,包括血管异常、胸廓畸形、纵隔病变或其他气道病变,也应考虑在内。如果可能,我们倾向于在同一手术中纠正气道病变和其他合并症,以防止多次手术及其伴随的更高风险。我们还强烈主张在所有颈部或胸部手术中使用喉返神经监测,以最大程度地降低声带功能和喉感觉受损的风险。需要评估这些干预措施对患者和护理人员生活质量的影响的研究,以充分了解 TBM 对这一具有挑战性的患者群体的影响。