Cicin Irfan, Oksuz Ergun, Karadurmus Nuri, Malhan Simten, Gumus Mahmut, Yilmaz Ulku, Cansever Levent, Cinarka Halit, Cetinkaya Erdogan, Kiyik Murat, Ozet Ahmet
Department of Medical Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Department of Family Medicine, Faculty of Medicine, Baskent University, Baglica Kampusu 06770, Etimesgut, Ankara, Turkey.
Health Econ Rev. 2021 Jun 26;11(1):22. doi: 10.1186/s13561-021-00322-2.
This study was designed to estimate economic burden of lung cancer in Turkey from payer perspective based on expert panel opinion on practice patterns in clinical practice.
In this cost of illness study, direct medical cost was calculated based on cost items related to outpatient visits, laboratory and radiological tests, hospitalizations/interventions, drug treatment, adverse events and metastasis. Indirect cost was calculated based on lost productivity due to early retirement, morbidity and premature death resulting from the illness, the value of lost productivity due to time spent by family caregivers and cost of formal caregivers.
Cost analysis revealed the total per patient annual direct medical cost for small cell lung cancer to be €8772), for non-small-cell lung cancer to be €10,167. Total annual direct medical cost was €497.9 million, total annual indirect medical cost was €1.1 billion and total economic burden of lung cancer was €1.6 billion. Hospitalization/interventions (41%) and indirect costs (68.6%) were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively.
Our findings indicate per patient direct medical costs of small cell lung cancer and non-small-cell lung cancer to be substantial and comparable, indicating the substantial economic burden of lung cancer in terms of both direct and indirect costs. Our findings indicate that hospitalization/interventions cost item and indirect costs were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively. Our findings emphasize the potential role of improved cancer prevention and early diagnosis strategies, by enabling cost savings related to drug treatment and metastasis management cost items, in sustainability of cancer treatments.
本研究旨在基于专家小组对临床实践模式的意见,从支付方角度评估土耳其肺癌的经济负担。
在这项疾病成本研究中,直接医疗成本根据与门诊就诊、实验室和放射学检查、住院/干预、药物治疗、不良事件和转移相关的成本项目进行计算。间接成本根据因提前退休、疾病导致的发病和过早死亡造成的生产力损失、家庭护理人员花费的时间导致的生产力损失价值以及正式护理人员的成本进行计算。
成本分析显示,小细胞肺癌患者每年的直接医疗成本总计为8772欧元,非小细胞肺癌为10167欧元。每年的直接医疗总成本为4.979亿欧元,每年的间接医疗总成本为11亿欧元,肺癌的总经济负担为16亿欧元。住院/干预(41%)和间接成本(68.6%)分别是直接成本总额和肺癌总体经济负担的主要成本驱动因素。
我们的研究结果表明,小细胞肺癌和非小细胞肺癌患者的直接医疗成本很高且相当,这表明肺癌在直接和间接成本方面都带来了巨大的经济负担。我们的研究结果表明,住院/干预成本项目和间接成本分别是直接成本总额和肺癌总体经济负担的主要成本驱动因素。我们的研究结果强调了改进癌症预防和早期诊断策略的潜在作用,通过节省与药物治疗和转移管理成本项目相关的费用,来实现癌症治疗的可持续性。