功能决定形式：基因表达与产前筛查。
Function Follows Form: Gene Expression and Prenatal Screening.
机构信息
Office of the Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA; Section on Prenatal Genomics and Fetal Therapy, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
出版信息
Trends Mol Med. 2021 Aug;27(8):725-727. doi: 10.1016/j.molmed.2021.06.001. Epub 2021 Jun 23.
Abstract
To date, prenatal testing has relied on imaging to determine fetal 'form' (anatomy). 'Function', as ascertained by measuring fetal or placental mRNA transcripts in maternal blood, has the potential to more precisely determine which pregnancies need closer monitoring and which babies should be delivered in special care settings.
摘要
迄今为止，产前检查一直依赖于影像学来确定胎儿的“形态”（解剖结构）。通过测量母体血液中的胎儿或胎盘 mRNA 转录本来确定“功能”，有可能更准确地确定哪些妊娠需要更密切的监测，以及哪些婴儿应该在特殊护理环境中分娩。
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