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以重度抑郁为表现的多发性硬化症:MRI扫描提示诊断,但CT扫描未提示。

Multiple sclerosis presenting as major depression: a diagnosis suggested by MRI scan but not CT scan.

作者信息

Salloway S, Price L H, Charney D S, Shapiro M

机构信息

Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. 06508.

出版信息

J Clin Psychiatry. 1988 Sep;49(9):364-6.

PMID:3417622
Abstract

A 43-year-old woman had melancholic major depression and mild incoordination. A magnetic resonance imaging (MRI) scan showed extensive lesions of the cerebral white matter that were not detected on a computed tomography (CT) scan. Since multiple sclerosis may initially present as depression, the differential sensitivities of MRI and CT scanning should be considered in deciding which neurodiagnostic studies should be conducted in depressed patients.

摘要

一名43岁女性患有忧郁型重度抑郁症且有轻度共济失调。磁共振成像(MRI)扫描显示脑白质有广泛病变,而计算机断层扫描(CT)未检测到这些病变。由于多发性硬化症最初可能表现为抑郁症,因此在决定对抑郁症患者应进行哪些神经诊断检查时,应考虑MRI和CT扫描的不同敏感性。

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J Neuropsychiatry Clin Neurosci. 2017 Winter;29(1):45-51. doi: 10.1176/appi.neuropsych.15120403. Epub 2016 Aug 19.
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Isolated progressive cognitive impairment and depression in a patient with neuroradiological features suggestive of multiple sclerosis.患者具有提示多发性硬化症的神经影像学特征,表现为孤立性进行性认知障碍和抑郁。
Neurol Sci. 2011 Aug;32(4):695-7. doi: 10.1007/s10072-011-0581-9. Epub 2011 Apr 16.
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Cognitive presentation of multiple sclerosis: evidence for a cortical variant.
多发性硬化的认知表现:皮质变异型的证据。
J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):872-7. doi: 10.1136/jnnp.74.7.872.