Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; CARE Arthritis, Edmonton, Alberta, Canada.
Semin Arthritis Rheum. 2021 Aug;51(4):933-939. doi: 10.1016/j.semarthrit.2021.05.013. Epub 2021 Jun 17.
To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA).
Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises.
In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion).
MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.
通过验证脊柱关节炎（SpA）中膝关节评分系统，实现全身 MRI 的基于区域的开发。
使用 2 种系统（OMERACT 外周关节和附着点的全身 MRI 炎症评分系统（MRI-WIPE）和膝关节炎症 MRI 评分系统（KIMRISS））对膝关节炎症性病变进行评估，共进行了 4 次迭代多读者练习。
在最后一次练习中，对于在前一次练习中具有最高一致性的读者，可靠性大多较好。骨炎和滑膜炎/渗出状态/变化的中位数两两单项测量 ICC 分别为 0.71/0.48（WIPE-骨炎）、0.48/0.77（WIPE-滑膜炎/渗出）、0.59/0.91（KIMRISS-骨炎）和 0.92/0.97（KIMRISS-滑膜炎/渗出）。SRM 分别为 0.74（WIPE-滑膜炎/渗出）和 0.78（KIMRISS-滑膜炎/渗出）。
MRI-WIPE 和 KIMRISS 均可用于 SpA 全身评估研究。
