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在健康老龄化、轻度认知障碍和痴呆的老年居民中,非优势单腿站立测试时间缩短与反复跌倒相关:若叶项目

Decreased Time on the Nondominant One-Leg Standing Test Associated with Repeated Falls in Older Residents with Healthy Aging, Mild Cognitive Impairment, and Dementia: The Wakuya Project.

作者信息

Kumai Keiichi, Kumai Mika, Takada Junko, Oonuma Jiro, Nakamura Kei, Meguro Kenichi

机构信息

Geriatric Behavioral Neurology Project, Tohoku University New Industry Creation Hatchery Center, Sendai, Japan.

Cyclotron RI Center, Tohoku University, Sendai, Japan.

出版信息

Dement Geriatr Cogn Dis Extra. 2021 May 21;11(2):122-128. doi: 10.1159/000516360. eCollection 2021 May-Aug.

Abstract

INTRODUCTION

The aim of this study is to clarify the association between repeated falls and the dominant/nondominant side in the open-eyed one-leg standing (OLS) test among people who are healthy or have mild cognitive impairment (MCI) or dementia in a community setting. We recruited 180 participants from 39 areas in the town of Wakuya.

METHODS

This is a cross-sectional study. Participants were classified into 3 Clinical Dementia Rating (CDR) groups, i.e., CDR 0 (healthy, = 71), CDR 0.5 (MCI, = 85), and CDR 1+ ( = 23), and they were investigated for motor function (grip strength, 6-m normal gait speed, timed up and go test, and OLS test) and falls during the past year.

RESULTS

Subjects with a CDR of 0.5 had higher rates of single and repeated falls (13.0 and 23.4%, respectively) than the CDR 0 group (12.1 and 4.5%, respectively), as did those in CDR 1+ group (15.0 and 30.0%). For the CDR 0.5 group, the frequency of falls was negatively (biologically meaningful direction) correlated with the left OLS time. No significant correlations with falls were found for other motor function tests. Another analysis separating the CDR 0.5 group into 2 subgroups (repeated falls vs. no or a single fall) also showed that the left OLS time was lower in subjects with repeated falls.

CONCLUSION

People with MCI who had fallen repeatedly in the year before the assessment had a significantly lower left OLS time compared to those who had not fallen or had had 1 fall with MCI. None of the other physical measures were associated with past repeat falls including OLS on the dominant right side. No such findings were noted in the CDR 0 and CDR 0+ groups.

摘要

引言

本研究旨在阐明在社区环境中,健康人群、轻度认知障碍(MCI)患者或痴呆患者在睁眼单腿站立(OLS)测试中反复跌倒与优势/非优势侧之间的关联。我们从若狭镇的39个地区招募了180名参与者。

方法

这是一项横断面研究。参与者被分为3个临床痴呆评定量表(CDR)组,即CDR 0(健康,n = 71)、CDR 0.5(MCI,n = 85)和CDR 1+(n = 23),并对他们的运动功能(握力、6米正常步态速度、计时起立行走测试和OLS测试)以及过去一年中的跌倒情况进行了调查。

结果

CDR为0.5的受试者单次和反复跌倒的发生率(分别为13.0%和23.4%)高于CDR 0组(分别为12.1%和4.5%),CDR 1+组的受试者也是如此(15.0%和30.0%)。对于CDR 0.5组,跌倒频率与左侧OLS时间呈负相关(具有生物学意义的方向)。在其他运动功能测试中未发现与跌倒有显著相关性。另一项将CDR 0.5组分为2个亚组(反复跌倒与未跌倒或单次跌倒)的分析也表明,反复跌倒的受试者左侧OLS时间较短。

结论

与未跌倒或仅有1次跌倒的MCI患者相比,在评估前一年中反复跌倒的MCI患者左侧OLS时间显著缩短。其他身体测量指标均与过去的反复跌倒无关,包括优势右侧的OLS。在CDR 0和CDR 0+组中未观察到此类结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9a2/8215974/b7e501f43901/dee-0011-0122-g01.jpg

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