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一名青少年头痛伴眼肌麻痹和颅神经功能缺损。

Ophthalmoplegia and cranial nerve deficits in an adolescent with headache.

作者信息

Corredor Margarita M, Holmberg Peter J

机构信息

Division of Pediatric Hospital Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

出版信息

SAGE Open Med Case Rep. 2021 Jun 12;9:2050313X211024487. doi: 10.1177/2050313X211024487. eCollection 2021.

DOI:10.1177/2050313X211024487
PMID:34178348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8202257/
Abstract

Tolosa-Hunt syndrome is an idiopathic, inflammatory condition involving the cavernous sinus and is characterized by unilateral, painful ophthalmoparesis. The condition often begins with retro-orbital pain followed by select cranial nerve involvement. We report the case of a 17-year-old female whose presentation with progressive left-sided headache and ophthalmoparesis culminated in the diagnosis of Tolosa-Hunt syndrome. While many of her signs and symptoms have been previously reported in the rare pediatric cases of Tolosa-Hunt syndrome described in the literature, this case illustrates a unique presentation involving cranial nerves V and VII in addition to the more commonly reported cranial nerve III, IV, and VI palsies.

摘要

托洛萨-亨特综合征是一种累及海绵窦的特发性炎症性疾病,其特征为单侧疼痛性眼肌麻痹。该病通常始于眶后疼痛,随后出现特定的颅神经受累。我们报告了一例17岁女性病例,其以进行性左侧头痛和眼肌麻痹为表现,最终被诊断为托洛萨-亨特综合征。虽然她的许多体征和症状在文献中描述的罕见小儿托洛萨-亨特综合征病例中已有报道,但该病例显示了一种独特的表现,除了更常见的颅神经III、IV和VI麻痹外,还累及颅神经V和VII。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9e8/8202257/a35fbc8c548b/10.1177_2050313X211024487-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9e8/8202257/a35fbc8c548b/10.1177_2050313X211024487-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9e8/8202257/a35fbc8c548b/10.1177_2050313X211024487-fig1.jpg

相似文献

1
Ophthalmoplegia and cranial nerve deficits in an adolescent with headache.一名青少年头痛伴眼肌麻痹和颅神经功能缺损。
SAGE Open Med Case Rep. 2021 Jun 12;9:2050313X211024487. doi: 10.1177/2050313X211024487. eCollection 2021.
2
Bilateral facial nerve involvement in a patient with Tolosa-Hunt syndrome.托洛萨-亨特综合征患者的双侧面神经受累。
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J Clin Med Res. 2020 Apr;12(4):266-268. doi: 10.14740/jocmr4123. Epub 2020 Mar 30.
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本文引用的文献

1
Successful treatment of pediatric Tolosa-Hunt syndrome with adalimumab.用阿达木单抗成功治疗儿童托洛萨-亨特综合征。
Eur J Rheumatol. 2020 Feb;7(Suppl1):S82-S84. doi: 10.5152/eurjrheum.2019.19149.
2
Tolosa-Hunt Syndrome: Clinical Manifestations in Children.托洛萨-亨特综合征:儿童的临床表现。
Pediatr Neurol. 2019 Oct;99:60-63. doi: 10.1016/j.pediatrneurol.2019.02.013. Epub 2019 Feb 20.
3
Bilateral Tolosa-Hunt syndrome mimicking pituitary adenoma.双侧托洛萨-亨特综合征表现类似垂体腺瘤。
Endocrine. 2017 Dec;58(3):582-586. doi: 10.1007/s12020-017-1422-2. Epub 2017 Oct 14.
4
Evaluation and Management of Tolosa-Hunt Syndrome in Children: A Clinical Update.儿童托洛萨-亨特综合征的评估与管理:临床最新进展
Pediatr Neurol. 2016 Sep;62:18-26. doi: 10.1016/j.pediatrneurol.2016.06.017. Epub 2016 Jun 25.
5
MRI findings in Tolosa-Hunt syndrome (THS).托洛萨-亨特综合征(THS)的磁共振成像(MRI)表现。
BMJ Case Rep. 2014 Nov 3;2014:bcr2014206629. doi: 10.1136/bcr-2014-206629.
6
Factors that influence Tolosa-Hunt syndrome and the short-term response to steroid pulse treatment.影响托洛萨-亨特综合征及对类固醇冲击治疗短期反应的因素。
J Neurol Sci. 2014 Jun 15;341(1-2):13-6. doi: 10.1016/j.jns.2014.03.031. Epub 2014 Mar 21.
7
Validation of ICHD-3 beta diagnostic criteria for 13.7 Tolosa-Hunt syndrome: Analysis of 77 cases of painful ophthalmoplegia.国际头痛疾病分类第三版(ICHD-3)β版诊断标准对13.7 托洛萨-亨特综合征的验证:77例疼痛性眼肌麻痹病例分析
Cephalalgia. 2014 Jul;34(8):624-32. doi: 10.1177/0333102413520082. Epub 2014 Jan 29.
8
Tolosa-Hunt syndrome--a rare cause of headache and ophthalmoplegia.托洛萨-亨特综合征——头痛和眼肌麻痹的罕见病因。
Lancet. 2013 Sep 7;382(9895):912. doi: 10.1016/S0140-6736(13)61442-7.
9
The International Classification of Headache Disorders, 3rd edition (beta version).《国际头痛疾病分类》第三版(试用版)
Cephalalgia. 2013 Jul;33(9):629-808. doi: 10.1177/0333102413485658.
10
Tolosa-Hunt syndrome masquerading as Gradenigo syndrome in a teenager.一名青少年中伪装成Gradenigo综合征的Tolosa-Hunt综合征。
Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1219-21. doi: 10.1016/j.ijporl.2013.04.023. Epub 2013 May 14.