Slattery Eric, White Andrew J, Gauthier Megan, Linscott Luke, Hirose Keiko
Departments of Otolaryngology, Radiology and Pediatrics, Washington University, 660 South Euclid Avenue, Campus Box 8115, St. Louis MO 63110, USA.
Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1219-21. doi: 10.1016/j.ijporl.2013.04.023. Epub 2013 May 14.
Tolosa-Hunt syndrome is an idiopathic chronic granulomatous inflammatory process commonly involving the cavernous sinus and the orbit. Symptoms include unilateral eye pain, ophthalmoplegia, headache, and facial pain in the distribution of the upper divisions of the trigeminal nerve and are highly responsive to steroid therapy. Gradenigo syndrome describes extension of a middle ear infection to the petrous apex, with trigeminal pain and ophthalmoplegia, typically responsive to antibiotics and often surgical drainage. We report a case of a 17 year-old girl with apparent Gradenigo syndrome, presenting with unilateral eye pain, abducens palsy, headache, hearing loss and serous otitis media, who was ultimately diagnosed with Tolosa-Hunt syndrome.
托洛萨-亨特综合征是一种特发性慢性肉芽肿性炎症过程，通常累及海绵窦和眼眶。症状包括单侧眼痛、眼肌麻痹、头痛以及三叉神经上支分布区域的面部疼痛，对类固醇治疗反应良好。Gradenigo综合征指中耳感染蔓延至岩尖，伴有三叉神经痛和眼肌麻痹，通常对抗生素治疗有效，且常需手术引流。我们报告一例17岁女孩，表现为明显的Gradenigo综合征，有单侧眼痛、展神经麻痹、头痛、听力丧失和浆液性中耳炎，最终被诊断为托洛萨-亨特综合征。
