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以恶性胸腔积液为表现的膀胱转移性腺癌：膀胱腺癌的一种罕见表现

Metastatic Adenocarcinoma of the Bladder Presenting as Malignant Pleural Effusion: A Rare Presentation of Bladder Adenocarcinoma.

作者信息

Ravikumar Rekha, Ross Astrid, Khan Muhammad S, Khan Ghazal, Desai Shaili

机构信息

Internal Medicine, Mercy Health, Toledo, USA.

Internal Medicine, University of Missouri, Kansas City, USA.

出版信息

Cureus. 2021 May 21;13(5):e15152. doi: 10.7759/cureus.15152.

DOI:10.7759/cureus.15152
PMID:34178487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8216572/
Abstract

Bladder cancers rarely are non-urothelial in origin. We present here, possibly the youngest case of a 35-year-old White female presenting with shortness of breath. She was found to have a malignant pleural effusion with unknown primary, eventually confirmed with genetic testing as metastatic adenocarcinoma of the urinary bladder with brain and lung metastasis. She was scheduled for palliative chemotherapy, however, passed away before it could be started. We highlight this rare case because of its unique presentation. Owing to similarity in receptors between adenocarcinoma and enteric cancer, similar chemotherapy regimens may be used for both. Unfortunately, treatment of metastatic disease remains highly controversial and needs to be studied further if there is an actual survival benefit to this or not.

摘要

膀胱癌很少起源于非尿路上皮。我们在此呈现可能是最年轻的病例，一名35岁白人女性，表现为呼吸急促。她被发现有不明原发灶的恶性胸腔积液，最终经基因检测确诊为膀胱转移性腺癌伴脑和肺转移。她原计划接受姑息化疗，但在化疗开始前去世。我们强调这个罕见病例是因其独特的表现。由于腺癌和肠癌受体相似，两者可能使用相似的化疗方案。不幸的是，转移性疾病的治疗仍存在很大争议，是否真的有生存获益需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/f5fd8f0d55a4/cureus-0013-00000015152-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/abb3a675a7b0/cureus-0013-00000015152-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/659c43d9be55/cureus-0013-00000015152-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/944a7bbe6ecf/cureus-0013-00000015152-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/b8d664b45f3d/cureus-0013-00000015152-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/f5fd8f0d55a4/cureus-0013-00000015152-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/abb3a675a7b0/cureus-0013-00000015152-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/659c43d9be55/cureus-0013-00000015152-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/944a7bbe6ecf/cureus-0013-00000015152-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/b8d664b45f3d/cureus-0013-00000015152-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f67/8216572/f5fd8f0d55a4/cureus-0013-00000015152-i05.jpg

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本文引用的文献

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Clin Genitourin Cancer. 2019 Oct;17(5):380-388. doi: 10.1016/j.clgc.2019.06.010. Epub 2019 Jun 26.
2
Advanced primary nonurachal adenocarcinoma of urinary bladder responding to modified FOLFOX6 and capecitabine: a case report.晚期原发性非脐尿管膀胱癌对改良FOLFOX6和卡培他滨治疗有反应：一例报告
Oxf Med Case Reports. 2018 Aug 11;2018(8):omy050. doi: 10.1093/omcr/omy050. eCollection 2018 Aug.
3
Malignant urachal neoplasms: A population-based study and systematic review of literature.
恶性脐尿管肿瘤：一项基于人群的研究及文献系统综述
Urol Oncol. 2017 Jan;35(1):33.e11-33.e19. doi: 10.1016/j.urolonc.2016.07.021. Epub 2016 Sep 1.
4
Adenocarcinoma of the urinary bladder.膀胱腺癌
Am J Clin Exp Urol. 2015 Aug 8;3(2):51-63. eCollection 2015.
5
Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance.原发性膀胱腺癌：鉴别诊断与临床相关性。
Arch Pathol Lab Med. 2013 Mar;137(3):371-81. doi: 10.5858/arpa.2012-0076-RA.
6
Urachal adenocarcinoma: a clinician's guide for treatment.脐尿管腺癌：治疗的临床医生指南。
Semin Oncol. 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011.
7
Sustained response of adenocarcinoma of the urinary bladder to FOLFOX plus bevacizumab.膀胱癌腺癌对 FOLFOX 加贝伐单抗的持续缓解。
Nat Rev Urol. 2011 May;8(5):282-5. doi: 10.1038/nrurol.2011.48. Epub 2011 Apr 12.
8
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9
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10
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Urol Oncol. 2006 Jan-Feb;24(1):13-20. doi: 10.1016/j.urolonc.2005.05.027.