Mumtaz Hashmi Hina, Shamim Nazia, Kumar Vinod, Idrees Sidra
Pediatrics and Child Health, Aga Khan University Hospital, Karachi, PAK.
Cureus. 2021 May 24;13(5):e15210. doi: 10.7759/cureus.15210.
Congenital melanocytic nevi arise from overgrowth or disrupted migration of melanocyte precursor in the neural crest. They are also known as coat-sleeve, stocking, bathing trunk or garment nevi. The colour ranges from brown to black, with the lesions presenting as flat to raised nevi. Lesions presenting at birth with a diameter greater than 20cm are labelled giant congenital melanocytic nevi. Risk increases with an increase in the number of satellite lesions near the giant nevus. Management includes regular clinical follow-up monitoring of changes in the lesion and surgical procedures in cases with risk of melanoma and psychological support. The purpose of this case presentation is to describe a rare issue of giant congenital melanocytic nevi in a newborn, along with a literature review and discussion on possible management options.
先天性黑素细胞痣起源于神经嵴中黑素细胞前体的过度生长或迁移中断。它们也被称为衣袖状、长袜状、泳装裤状或服饰样痣。颜色从棕色到黑色不等,病变表现为扁平至隆起的痣。出生时直径大于20cm的病变被标记为巨大先天性黑素细胞痣。巨大痣附近卫星病灶数量增加,风险也随之增加。管理措施包括定期临床随访监测病变变化,对有黑素瘤风险的病例进行手术治疗以及提供心理支持。本病例报告的目的是描述一名新生儿罕见的巨大先天性黑素细胞痣问题,并进行文献综述以及讨论可能的管理方案。