All India Institute of Medical Sciences Rishikesh, Rishikesh, Uttarakhand, India.
Banaras Hindu University, Varanasi, UP, India.
Int J Low Extrem Wounds. 2023 Sep;22(3):612-615. doi: 10.1177/15347346211028687. Epub 2021 Jun 28.
Marjolin's ulcer (MU) with rapid progression and multiple distant metastases is rare. We report a case of an MU of the thigh developing in a postburn scar, which after successful R0 resection developed multiple bony and visceral metastasis to femur, vertebra, skull, lung, and liver within 3 months of excision. We highlight the "hurricane-like" recurrence in an MU, which is unusual for the metachronous disease. We stress that MUs, unlike conventional wisdom, need a thorough metastatic workup at presentation, and prognostication of a possible rapidly progressive course after surgery which may lead to grave prognosis and mortality.
马约林溃疡(MU)具有快速进展和多发性远处转移的特点,较为罕见。我们报告了一例发生于大腿烧伤瘢痕处的 MU,在成功进行了 R0 切除术后 3 个月内,迅速发生了股骨、椎体、颅骨、肺和肝的多发性骨转移和内脏转移。我们强调了 MU 中罕见的“飓风样”复发,这与该疾病的异时性特征不同。我们强调,与传统观念不同,MU 在初次就诊时需要进行彻底的转移评估,以预测手术后可能出现的快速进展过程,这可能导致严重的预后和死亡率。