Angle Orthod. 2021 Jul 1;91(4):555-563. doi: 10.2319/080320-678.1.
Orthognathic surgery in patients with craniofacial osteopetrosis, a condition associated with osteoclast dysfunction, is usually avoided because of the risk of osteomyelitis. A 19-year-old woman presented with the chief complaint of severe malocclusion and anterior crossbite. After radiographic evaluation, craniofacial osteopetrosis was diagnosed. Surgical-orthodontic treatment was performed after meticulous history taking and verification of normal bone turnover using bone-metabolism markers for endocrine evaluation. Favorable esthetic and functional outcomes were achieved.
颅颌面骨硬化症患者的正颌手术通常因骨髓炎风险而被避免,这种病症与破骨细胞功能障碍相关。一位 19 岁的女性因严重的错颌和前牙反颌来就诊。经过影像学评估,诊断为颅颌面骨硬化症。通过详细的病史采集和骨代谢标志物的骨转换验证,进行了外科-正畸治疗,用于内分泌评估。获得了满意的美观和功能效果。