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Surgical-orthodontic treatment for severe malocclusion in a patient with osteopetrosis and bilateral cleft lip and palate.骨硬化症伴双侧唇腭裂患者严重错颌畸形的外科-正畸治疗。
Angle Orthod. 2021 Jul 1;91(4):555-563. doi: 10.2319/080320-678.1.
2
Anterior crossbite, dental arch dimensions, and later need for orthognathic surgery in 6-year-old children with unilateral cleft lip and palate.单侧唇腭裂6岁儿童的前牙反合、牙弓尺寸及后期正颌手术需求
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Orthodontic camouflage treatment for a patient with bilateral cleft lip and palate, bilateral crossbite, and microdontic maxillary lateral incisors.正畸掩饰性治疗双侧唇腭裂、双侧反颌、上颌侧切牙过小患者。
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Orthognathic surgery for the cleft lip and palate patient.唇腭裂患者的正颌外科手术
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Orthodontic Treatment Combined with Orthognathic Surgery and Simultaneous Alveolar Bone Graft of a Unilateral Complete Cleft Lip and Palate Patient: A Case Report.正畸治疗联合正颌手术及同期牙槽骨植骨治疗单侧完全性唇腭裂患者：病例报告
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Comprehensive Review of Prevention and Management Strategies for Medication-related Osteonecrosis of the Jaw (MRONJ).颌骨药物性骨坏死（MRONJ）预防与管理策略的综合综述
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本文引用的文献

1
Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.成骨不全症的诊断与管理：成骨不全症工作组的共识指南。
J Clin Endocrinol Metab. 2017 Sep 1;102(9):3111-3123. doi: 10.1210/jc.2017-01127.
2
Periodontal profile and radiographic characterization of the jaws in a patient with autosomal dominant osteopetrosis.一名常染色体显性遗传性骨硬化症患者颌骨的牙周情况及影像学特征
Endocrinol Diabetes Metab Case Rep. 2017 Apr 21;2017. doi: 10.1530/EDM-16-0106. eCollection 2017.
3
A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ?一项多中心回顾性研究，探讨了接受口服双膦酸盐治疗的拔牙后药物相关性颌骨坏死的相关风险因素：原发伤口闭合和药物暂停真的能预防 MRONJ 吗？
Osteoporos Int. 2017 Aug;28(8):2465-2473. doi: 10.1007/s00198-017-4063-7. Epub 2017 Apr 27.
4
The Rare Bone Disease Working Group: report from the 2016 American Society for Bone and Mineral Research Annual Meeting.罕见骨病工作组：2016 年美国骨矿研究学会年会报告。
Bone. 2017 Sep;102:80-84. doi: 10.1016/j.bone.2017.01.021. Epub 2017 Jan 20.
5
Osteomyelitis of Maxilla in Infantile Osteopetrosis: A Case Report with Review of Literature.婴儿骨硬化症中的上颌骨骨髓炎：一例病例报告并文献复习
Int J Clin Pediatr Dent. 2011 May-Aug;4(2):125-8. doi: 10.5005/jp-journals-10005-1095. Epub 2010 Apr 15.
6
Dental implants and osteomyelitis in a patient with osteopetrosis.一名石骨症患者的牙种植体与骨髓炎
Quintessence Int. 2014 Oct;45(9):765-8. doi: 10.3290/j.qi.a32443.
7
Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population.西非人群中 60 例下颌骨和上颌骨极度骨髓炎和骨坏死。
Int J Oral Maxillofac Surg. 2012 Aug;41(8):978-85. doi: 10.1016/j.ijom.2012.04.022. Epub 2012 May 29.
8
The nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in dental implant patients: a South Australian case series.牙种植患者中双膦酸盐相关颌骨坏死的性质和发生率：南澳大利亚病例系列
J Oral Maxillofac Surg. 2010 Feb;68(2):337-43. doi: 10.1016/j.joms.2009.09.037.
9
Marble bone disease: a review of osteopetrosis and its oral health implications for dentists.大理石骨病：骨硬化症综述及其对牙医口腔健康的影响
J Can Dent Assoc. 2007 Nov;73(9):839-43.
10
Autosomal dominant osteopetrosis and maxillomandibular osteomyelitis.常染色体显性遗传性骨硬化症与颌骨骨髓炎
Am J Otolaryngol. 2005 Jul-Aug;26(4):275-8. doi: 10.1016/j.amjoto.2005.01.007.

骨硬化症伴双侧唇腭裂患者严重错颌畸形的外科-正畸治疗。

Surgical-orthodontic treatment for severe malocclusion in a patient with osteopetrosis and bilateral cleft lip and palate.

出版信息

Angle Orthod. 2021 Jul 1;91(4):555-563. doi: 10.2319/080320-678.1.

DOI:10.2319/080320-678.1
PMID:34181720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8259756/
Abstract

Orthognathic surgery in patients with craniofacial osteopetrosis, a condition associated with osteoclast dysfunction, is usually avoided because of the risk of osteomyelitis. A 19-year-old woman presented with the chief complaint of severe malocclusion and anterior crossbite. After radiographic evaluation, craniofacial osteopetrosis was diagnosed. Surgical-orthodontic treatment was performed after meticulous history taking and verification of normal bone turnover using bone-metabolism markers for endocrine evaluation. Favorable esthetic and functional outcomes were achieved.

摘要

颅颌面骨硬化症患者的正颌手术通常因骨髓炎风险而被避免，这种病症与破骨细胞功能障碍相关。一位 19 岁的女性因严重的错颌和前牙反颌来就诊。经过影像学评估，诊断为颅颌面骨硬化症。通过详细的病史采集和骨代谢标志物的骨转换验证，进行了外科-正畸治疗，用于内分泌评估。获得了满意的美观和功能效果。