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西非人群中 60 例下颌骨和上颌骨极度骨髓炎和骨坏死。

Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population.

机构信息

Mercy Ships, Lindale, TX, USA.

出版信息

Int J Oral Maxillofac Surg. 2012 Aug;41(8):978-85. doi: 10.1016/j.ijom.2012.04.022. Epub 2012 May 29.

DOI:10.1016/j.ijom.2012.04.022
PMID:22652445
Abstract

A description of 60 cases of extreme osteonecrosis and osteomyelitis of the jaws is presented. The patients attended the dental clinics of the medical charity organisation Mercy Ships, over a 2.5-year period when the hospital ship the 'Africa Mercy' was docked in the West African countries of Liberia, Benin and Togo. Possible reasons for the development of these clinical conditions are discussed including aetiologies, genetics (coagulopathies, osteopetrosis), Gorham's disease, infective conditions (tuberculosis, herpes zoster, HIV infection, osteomyelitis), toxicity (bisphosphonates, spider bites), and environmental effects (phossy jaw, radium jaw). The possible causes of these cases of osteonecrosis and osteomyelitis of the jaw are under investigation.

摘要

现描述了 60 例极端颌骨坏死性骨炎病例。这些患者在 Mercy Ships 慈善医疗机构的牙科诊所就诊, Mercy Ships 慈善医疗船“非洲慈悲号”在利比里亚、贝宁和多哥这三个西非国家停靠的 2.5 年期间,该医院收治了这些患者。讨论了这些临床病症发展的可能原因,包括病因、遗传学(凝血功能障碍、石骨症)、Gorham 病、感染性疾病(结核病、带状疱疹、HIV 感染、骨髓炎)、毒性(双膦酸盐、蜘蛛咬伤)和环境影响(磷毒性颌骨、镭毒性颌骨)。这些颌骨坏死性骨炎病例的可能病因正在调查中。

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