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深吸气屏气放疗在左侧乳腺癌保乳术后患者中的应用。

Deep-inspiration breath hold radiotherapy in patients with left-sided breast cancer after partial mastectomy.

出版信息

Rozhl Chir. 2021 Spring;100(4):180-185. doi: 10.33699/PIS.2021.100.4..

DOI:10.33699/PIS.2021.100.4.
PMID:34182760
Abstract

The purpose of this study was to compare the radiation dose to organs at risk for deep-inspiration breath hold (DIBH) and free-breathing (FB) radiotherapy in patients with lef-sided breast cancer undergoing adjuvant radiotherapy after partial mastectomy.  Methods: One hundred patients with left-sided breast cancer underwent DIBH and FB planning computed tomography scans, and the 2 techniques were compared. Dose-volume histograms were analyzed for heart, left anterior descending coronary artery (LAD), and left lung.  Results: Radiation dose to heart, LAD, and left lung was significantly lower for DIBH than for free breathing plans. The median mean heart dose for DIBH technique in comparison with FB was 1.21 Gy, and 3.22 Gy respectively; for LAD, 4.67 versus 24.71 Gy; and for left lung 8.32 Gy versus 9.99 Gy.  Conclusion: DIBH is an effective technique to reduce cardiac and lung radiation exposure.

摘要

本研究旨在比较左侧乳腺癌保乳术后辅助放疗中深吸气屏气(DIBH)和自由呼吸(FB)放疗的风险器官的辐射剂量。方法:100 例左侧乳腺癌患者行 DIBH 和 FB 计划 CT 扫描,比较两种技术。分析了心脏、左前降支冠状动脉(LAD)和左肺的剂量-体积直方图。结果:DIBH 组的心脏、LAD 和左肺的辐射剂量明显低于 FB 组。DIBH 组与 FB 组相比,心脏平均剂量中位数分别为 1.21 Gy 和 3.22 Gy;LAD 分别为 4.67 Gy 和 24.71 Gy;左肺分别为 8.32 Gy 和 9.99 Gy。结论:DIBH 是降低心脏和肺辐射暴露的有效技术。

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引用本文的文献

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Comparison of Deep Inspiration Breath Hold Versus Free Breathing in Radiotherapy for Left Sided Breast Cancer.左侧乳腺癌放疗中深吸气屏气与自由呼吸的比较
Front Oncol. 2022 Apr 21;12:845037. doi: 10.3389/fonc.2022.845037. eCollection 2022.