From the Departments of Radiology.
Orthopedic Surgery, Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Clin Nucl Med. 2022 Jan 1;47(1):e98-e100. doi: 10.1097/RLU.0000000000003783.
Granulocyte colony-stimulating factor (G-CSF)-producing tumors are malignant tumors associated with a poor prognosis, and G-CSF-producing liposarcoma is particularly rare. We report a case of G-CSF-producing dedifferentiated liposarcoma. 18F-FDG PET/CT showed abnormal 18F-FDG uptake throughout the bone marrow and in the primary site. When a diffuse bone marrow 18F-FDG uptake was observed on 18F-FDG PET/CT, G-CSF-producing dedifferentiated liposarcoma should be included in the differential diagnosis.
粒细胞集落刺激因子（G-CSF）产生的肿瘤是与预后不良相关的恶性肿瘤，而 G-CSF 产生的脂肪肉瘤则特别罕见。我们报告了一例 G-CSF 产生的去分化脂肪肉瘤。18F-FDG PET/CT 显示整个骨髓和原发部位异常摄取 18F-FDG。当 18F-FDG PET/CT 上观察到弥漫性骨髓 18F-FDG 摄取时，应将 G-CSF 产生的去分化脂肪肉瘤纳入鉴别诊断。
