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上颌外周牙源性影细胞肿瘤。

Peripheral Dentinogenic Ghost Cell Tumor of the Maxilla.

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kocaeli University, Turkey.

出版信息

J Craniofac Surg. 2021;32(8):e739-e740. doi: 10.1097/SCS.0000000000007719.

Abstract

Dentinogenic ghost cell tumor (DGCT) is an uncommon locally invasive odontogenic tumor, representing 1.9% to 2.1% of all odontogenic tumors. The main microscopic features of DGCT are an ameloblastoma-like odontogenic epithelial proliferation with sheets of ghost cells and dentinoid material formation. The peripheral variant of this clinical rarity, which represents a less aggressive behavior than central lesions, mostly affects the anterior region of both jaws. In this case report, the authors present a DGCT that was observed in the maxillary posterior region in a 59-year-old female patient. The patient presented with pain and nodular swelling in the right maxillary molar region, which extended from the buccal vestibule to the edentulous area. Additionally, there was a destruction of the underlying bone, as seen radiographically. This case report includes the clinical, radiological, and histopathological features of the lesion, which was diagnosed as a peripheral DGCT without any evidence of recurrence in the 2 years after excision.

摘要

牙源性影细胞肿瘤(DGCT)是一种不常见的局部侵袭性牙源性肿瘤,占所有牙源性肿瘤的 1.9%至 2.1%。DGCT 的主要显微镜特征是具有成釉细胞瘤样牙源性上皮增生,伴有鬼影细胞和成牙本质物质形成的片状结构。这种临床罕见病的外周变体比中央病变具有更低的侵袭性,主要影响上下颌的前区。在本病例报告中,作者展示了一例发生在 59 岁女性患者上颌后区的 DGCT。患者表现为右侧上颌磨牙区疼痛和结节性肿胀,从颊侧前庭延伸至无牙区。此外,影像学可见下方骨破坏。本病例报告包括病变的临床、放射学和组织病理学特征,诊断为外周型 DGCT,切除后 2 年内无复发证据。

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