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[神经可塑性机制在前庭疾病静态-动态障碍代偿中的意义]

[The significance of neuroplastic mechanisms in compensation of statodynamic impairments during vestibular disorders].

作者信息

Samartsev I N, Zhivolupov S A

机构信息

Kirov Military Medical Academy, St. Petersburg, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(5):165-172. doi: 10.17116/jnevro2021121051165.

Abstract

The process of balance restoration in patients with the vestibular disorders is known as «vestibular compensation». It is obvious nowadays that this phenomenon is very complex and is associated with the deep brain neuroplastic changes involving reinnervation, habituation and adaptation. The research of the last decades has shown some fundamental physiologic mechanisms that form the basis of neuroplasticity, establish the staging of ongoing transformations and analyze the opportunity to improve and/or accelerate vestibular compensation with the help of vestibular rehabilitation and contemporary medications such as betaserc long.

摘要

前庭疾病患者恢复平衡的过程被称为“前庭代偿”。如今很明显,这种现象非常复杂,并且与涉及再支配、习惯化和适应的深部脑区神经可塑性变化有关。过去几十年的研究揭示了一些构成神经可塑性基础的基本生理机制,确定了正在进行的转变的阶段,并分析了借助前庭康复以及诸如倍他司汀长效制剂等现代药物改善和/或加速前庭代偿的可能性。

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