Pulsipher Dalin T, Rettig Eman K, Krapf Erica M, Stanford Lisa D
NeuroDevelopmental Science Center, Division of Neurobehavioral Health, Akron Children's Hospital, Akron, Ohio, USA.
Brain Inj. 2021 Jul 3;35(8):964-970. doi: 10.1080/02699052.2021.1942550. Epub 2021 Jun 29.
To evaluate the frequency and severity of post-concussive symptoms in youth with a history of concussion relative to youth without concussion who had another medical diagnosis, as well as compare the correlations between post-concussive and depressive symptoms between groups. We hypothesized comparable symptom reporting and correlations in each group.
A total of 564 youth ages 8-18 years were assessed regarding post-concussive symptoms. A subset of youth ( = 360) were compared on correlations between post-concussive and depressive symptoms. Non-parametric statistics were used for most analyses.
Youth with concussion reported a comparable number of post-concussive and depressive symptoms as youth with another medical condition without concussion. However, those with concussion reported greater post-concussive symptom severity (but small effect sizes). Relationships between post-concussive and depressive symptoms were comparable for both groups, but for those who sustained a concussion, the correlation was significantly stronger for females than males.
This study further demonstrates that post-concussive symptoms are nonspecific and provide little functional utility. Post-concussive and depressive symptoms are strongly correlated, particularly in females with concussion. Psychiatric comorbidities and other medical diagnoses should be assessed pre-injury because both affect interpretation of post-concussive symptom reports.
评估有脑震荡病史的青少年与患有其他医学诊断但无脑震荡病史的青少年相比，脑震荡后症状的发生频率和严重程度，并比较两组之间脑震荡后症状与抑郁症状的相关性。我们假设每组的症状报告和相关性具有可比性。
对总共564名8至18岁的青少年进行了脑震荡后症状评估。对一部分青少年（n = 360）的脑震荡后症状与抑郁症状的相关性进行了比较。大多数分析采用非参数统计。
有脑震荡的青少年报告的脑震荡后症状和抑郁症状数量与患有其他医学疾病但无脑震荡的青少年相当。然而，有脑震荡的青少年报告的脑震荡后症状严重程度更高（但效应量较小）。两组的脑震荡后症状与抑郁症状之间的关系具有可比性，但对于遭受脑震荡的青少年，女性的相关性明显强于男性。
本研究进一步表明，脑震荡后症状是非特异性的，功能效用不大。脑震荡后症状与抑郁症状密切相关，尤其是在患有脑震荡的女性中。受伤前应评估精神共病和其他医学诊断，因为两者都会影响对脑震荡后症状报告的解读。
