Zúñiga Marcela, Passalacqua Stephanía, Benadof Dona, Conca Natalia, Acuña Mirta
Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Laboratorio de Microbiología, Hospital Roberto del Río, Santiago, Chile.
Rev Chilena Infectol. 2021 Apr;38(2):300-302. doi: 10.4067/S0716-10182021000200300.
Staphylococcus aureus colonizes the nasopharynx in one third of healthy individuals and is also responsible for several infections in pediatrics such as endocarditis, pneumonia and osteoarticular infections. It has several virulence mechanisms, such as Panton Valentine leukocidin (PVL), which is an exotoxin that causes cell death. It is commonly related to methicillin-resistant Staphylococcus aureus (MRSA) and more serious pulmonary and musculoskeletal infections. However, PVL is not exclusive to MRSA. Two clinical cases of patients with infection by methicillin-sensitive Staphylococcus aureus producing this exotoxin are presented.
三分之一的健康个体鼻咽部会定植金黄色葡萄球菌，它还会引发儿科的多种感染，如心内膜炎、肺炎和骨关节炎感染。它有多种致病机制，比如杀白细胞素（PVL），这是一种可导致细胞死亡的外毒素。它通常与耐甲氧西林金黄色葡萄球菌（MRSA）以及更严重的肺部和肌肉骨骼感染有关。然而，PVL并非MRSA所特有。本文介绍了两例由产生这种外毒素的甲氧西林敏感金黄色葡萄球菌感染患者的临床病例。
